Biocompatible polymer-nanoparticles-based bimodal imaging contrast agents for the labeling and tracking of dendritic cells

Cited 106 time in scopus
Metadata Downloads

Full metadata record

DC FieldValueLanguage
dc.contributor.authorYong Taik Lim-
dc.contributor.authorYoung Woock Noh-
dc.contributor.authorJeong Hyun Han-
dc.contributor.authorQ Y Cai-
dc.contributor.authorK H Yoon-
dc.contributor.authorBong Hyun Chung-
dc.date.accessioned2017-04-19T09:11:52Z-
dc.date.available2017-04-19T09:11:52Z-
dc.date.issued2008-
dc.identifier.issn1613-6810-
dc.identifier.uri10.1002/smll.200800582ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/8633-
dc.description.abstractDisulfonated inldocyanine green (ICG) was chosen as the optical modality in the synthesis of bimodal imaging contrast agents for the labeling and tracking of dendritic cells (DC). ICG and iron oxide nanoparticles were encapsulated by using biocompatible polymer poly(lactide-co-glycolide) (PLGA), and ICG molecules were non-covalently bond with human serum albumin (HSA). The results show that binding of HSA proteins with ICG would enhance the compatibility of PLGA in the organic phase with ICG in the aqueous phase. The PLGA nanoparticles are found to generate MR contrast signals, and the increase in the contamination of the nanoparticles led to a decrease in the signal integrity. It is confirmed that PLGA nanoparticles containing iron oxide nanoparticles internalized into DCs, while a decrease in the signal integrity of DCs labels with PLGA nanoparticles is also observed.-
dc.publisherWiley-
dc.titleBiocompatible polymer-nanoparticles-based bimodal imaging contrast agents for the labeling and tracking of dendritic cells-
dc.title.alternativeBiocompatible polymer-nanoparticles-based bimodal imaging contrast agents for the labeling and tracking of dendritic cells-
dc.typeArticle-
dc.citation.titleSmall-
dc.citation.number10-
dc.citation.endPage1645-
dc.citation.startPage1640-
dc.citation.volume4-
dc.contributor.affiliatedAuthorYong Taik Lim-
dc.contributor.affiliatedAuthorYoung Woock Noh-
dc.contributor.affiliatedAuthorJeong Hyun Han-
dc.contributor.affiliatedAuthorBong Hyun Chung-
dc.contributor.alternativeName임용택-
dc.contributor.alternativeName노영욱-
dc.contributor.alternativeName한정현-
dc.contributor.alternativeNameCai-
dc.contributor.alternativeName윤권하-
dc.contributor.alternativeName정봉현-
dc.identifier.bibliographicCitationSmall, vol. 4, no. 10, pp. 1640-1645-
dc.identifier.doi10.1002/smll.200800582-
dc.subject.keywordBiocompatible materials-
dc.subject.keywordContrast agents-
dc.subject.keywordFluorescence-
dc.subject.keywordMagnetic resonance imaging-
dc.subject.keywordNanoparticles-
dc.subject.localBiocompatible materials-
dc.subject.localContrast agents-
dc.subject.localcontrast agent-
dc.subject.localfluorescence-
dc.subject.localFluorescence-
dc.subject.localmagnetic resonance imaging (MRI)-
dc.subject.localMagnetic Resonance Imaging-
dc.subject.localmagnetic resonance imaging-
dc.subject.localMagnetic resonance imaging-
dc.subject.localMRI-
dc.subject.localMagnetic resonance imaging (MRI)-
dc.subject.localNanoparticles-
dc.subject.localNanoparticle-
dc.subject.localnanoparticle-
dc.description.journalClassY-
Appears in Collections:
1. Journal Articles > Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.