Open Access@KRIBBDivision of Research on National ChallengesInfectious Disease Research Center1. Journal Articles
Macrolactin S, a new antibacterial agent with FabG-inhibitory activity from Bacillus sp. AT28 = 바실러스균으로부터 분리한 FabG저해활성을 갖는 새로운 항세균물질 Macrolactin S
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Sohn Mi Jin | - |
| dc.contributor.author | ChangJi Zheng | - |
| dc.contributor.author | Won Gon Kim | - |
| dc.date.accessioned | 2017-04-19T09:12:43Z | - |
| dc.date.available | 2017-04-19T09:12:43Z | - |
| dc.date.issued | 2008 | - |
| dc.identifier.issn | 0021-8820 | - |
| dc.identifier.uri | 10.1038/ja.2008.98 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/8771 | - |
| dc.description.abstract | In the course of screening for FabG inhibitors from microbial sources, a new 24-membered ring lactone named macrolactin S, along with the known compound macrolactin B, has been isolated from the mycelium of liquid fermentation cultures of Bacillus sp. AT28. The structure of macrolactin S was determined on the basis of MS and NMR data. Macrolactin S showed a dose-dependent inhibition of Staphylococcus aureus FabG, not inhibiting S. aureus FabI. Also macrolactin S inhibited the growth of 5. aureus, Bacillus subtilis, and Escherichia coli. | - |
| dc.publisher | Springer-Nature Pub Group | - |
| dc.title | Macrolactin S, a new antibacterial agent with FabG-inhibitory activity from Bacillus sp. AT28 = 바실러스균으로부터 분리한 FabG저해활성을 갖는 새로운 항세균물질 Macrolactin S | - |
| dc.title.alternative | Macrolactin S, a new antibacterial agent with FabG-inhibitory activity from Bacillus sp. AT28 | - |
| dc.type | Article | - |
| dc.citation.title | Journal of Antibiotics | - |
| dc.citation.number | 11 | - |
| dc.citation.endPage | 691 | - |
| dc.citation.startPage | 687 | - |
| dc.citation.volume | 61 | - |
| dc.contributor.affiliatedAuthor | Sohn Mi Jin | - |
| dc.contributor.affiliatedAuthor | ChangJi Zheng | - |
| dc.contributor.affiliatedAuthor | Won Gon Kim | - |
| dc.contributor.alternativeName | 손미진 | - |
| dc.contributor.alternativeName | 정창길 | - |
| dc.contributor.alternativeName | 김원곤 | - |
| dc.identifier.bibliographicCitation | Journal of Antibiotics, vol. 61, no. 11, pp. 687-691 | - |
| dc.identifier.doi | 10.1038/ja.2008.98 | - |
| dc.subject.keyword | Antibacterial | - |
| dc.subject.keyword | Bacillus | - |
| dc.subject.keyword | FabG | - |
| dc.subject.keyword | Macrolactin | - |
| dc.subject.keyword | Staphylococcus aureus | - |
| dc.subject.local | Antibacterial | - |
| dc.subject.local | Antibacterials | - |
| dc.subject.local | antibacterial | - |
| dc.subject.local | Anti-bacterial | - |
| dc.subject.local | antibacterials | - |
| dc.subject.local | Bacillus | - |
| dc.subject.local | bacillus | - |
| dc.subject.local | FabG | - |
| dc.subject.local | Macrolactin | - |
| dc.subject.local | Staphylococcus aureus | - |
| dc.subject.local | staphylococcus aureus | - |
| dc.description.journalClass | Y | - |
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