Identification of novel acetylenic alcohols and a new dihydrothiopyranone from the tropical sponge Reniochalina sp.

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Title
Identification of novel acetylenic alcohols and a new dihydrothiopyranone from the tropical sponge Reniochalina sp.
Author(s)
H S Lee; J H Lee; H Won; Song Kyu Park; Hwan Mook Kim; H J Shin; H S Park; C J Sim; H K Kim
Bibliographic Citation
Lipids, vol. 44, no. 1, pp. 71-75
Publication Year
2009
Abstract
Two new acetylenic alcohols (1-2) and a new dihydrothiopyranone (3) were isolated from the tropical sponge Reniochalina sp. Their structures were determined by spectroscopic and chemical methods to be (3R)-hydroxyoctatriacont- (4E)-en-1-yne (1), 5-hydroxyheptatriacont-(3Z)-en-1-yne (2) and 2-hexadecyl-2,3-dihydrothiopyran-4-one (3). The acetylenic alcohol (1) exhibited significant growth inhibitory effect against human tumor cell lines.
Keyword
Reniochalina sp.Tropical spongeGrowth inhibitionAcetylenic alcoholDihydrothiopyranone
ISSN
0024-4201
Publisher
Wiley
DOI
http://dx.doi.org/10.1007/s11745-008-3249-3
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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