돌단풍(Aceriphyllum rossii)에서 분리한 플라보노이드의 항암활성 = Anti-cancer activity of flavonoids from Aceriphyllum rossii

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dc.contributor.authorE M Ahn-
dc.contributor.authorJ T Han-
dc.contributor.authorByoung-Mog Kwon-
dc.contributor.authorS H Kim-
dc.contributor.authorN I Baek-
dc.date.accessioned2017-04-19T09:13:10Z-
dc.date.available2017-04-19T09:13:10Z-
dc.date.issued2008-
dc.identifier.issnI000-0171-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/8816-
dc.description.abstractThe methanol extract from the aerial parts of Aceriphyllum rossii was fractionated into ethyl acetate, n-BuOH and H2O layers through solvent fractionation. Repeated silica gel column chromatography of EtOAc and n-BuOH layers afforded five flavonol glycosides. They were identified as astragalin (1), kaempferol 3-O-α-L-rhamnopyranosyl (1→6)-β-D-glucopyranoside (2), rutin (3), kaempferol 3-O-α-L-rhamnopyranosyl (1→4)-α-L-rhamnopyranosyl (1→6)-β-D-glucopyranoside (4), and quercetin 3-O-α-L-rhamnopyranosyl (1→4)-α-L-rhamnopyranosyl (1→6)-β-D-glucopyranoside (5) on the basis of spectroscopic data. All of them showed an inhibition in farnesyl protein tranferase (FPTase) activity, and rutin (3) inhibited the growth of rat H-ras cell and the cell migration of human umbilical vein endothelial cells (HUVECs).-
dc.publisherKorea Soc-Assoc-Inst-
dc.title돌단풍(Aceriphyllum rossii)에서 분리한 플라보노이드의 항암활성 = Anti-cancer activity of flavonoids from Aceriphyllum rossii-
dc.title.alternativeAnti-cancer activity of flavonoids from Aceriphyllum rossii-
dc.typeArticle-
dc.citation.titleJournal of Korean Society for Applied Biological Chemistry-
dc.citation.number4-
dc.citation.endPage315-
dc.citation.startPage309-
dc.citation.volume51-
dc.contributor.affiliatedAuthorByoung-Mog Kwon-
dc.contributor.alternativeName안은미-
dc.contributor.alternativeName한재택-
dc.contributor.alternativeName권병목-
dc.contributor.alternativeName김성훈-
dc.contributor.alternativeName백남인-
dc.identifier.bibliographicCitationJournal of Korean Society for Applied Biological Chemistry, vol. 51, no. 4, pp. 309-315-
dc.identifier.doi10.3839/jksabc.2008.054-
dc.subject.keywordaceriphyllum rossii-
dc.subject.keywordanti-cancer-
dc.subject.keywordcell migration-
dc.subject.keywordflavonol glycoside-
dc.subject.keywordFPTase-
dc.subject.keywordH-ras-
dc.subject.localAceriphyllum rossii-
dc.subject.localaceriphyllum rossii-
dc.subject.localAnti-cancer-
dc.subject.localAnticancer-
dc.subject.localanti-cancer-
dc.subject.localanticancer-
dc.subject.localAnti-Cancer-
dc.subject.localcell migration-
dc.subject.localCell migration-
dc.subject.localFlavonol glycosides-
dc.subject.localflavonol glycoside-
dc.subject.localFPTase-
dc.subject.localH-Ras-
dc.subject.localH-ras-
dc.description.journalClassN-
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