DC Field | Value | Language |
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dc.contributor.author | Hwa-Jung Choi | - |
dc.contributor.author | C H Lim | - |
dc.contributor.author | J H Song | - |
dc.contributor.author | S H Baek | - |
dc.contributor.author | Dur Han Kwon | - |
dc.date.accessioned | 2017-04-19T09:13:10Z | - |
dc.date.available | 2017-04-19T09:13:10Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0944-7113 | - |
dc.identifier.uri | 10.1016/j.phymed.2008.10.012 | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/8818 | - |
dc.description.abstract | RNA viruses are a major source of respiratory diseases worldwide. The lack of effective therapeutical treatment underlines the importance of research for new antiviral compounds. Raoulic acid is a principal ingredient of the plant Raoulia australis Hook. F. Antiviral assay using cytopathic effect (CPE) reduction method showed that raoulic acid possessed strong antiviral activity against human rhinovirus 2 (HRV2) with a 50% inhibition concentration (IC50) value of less than 0.1 μg/ml, human rhinovirus 3 (HRV3) with a IC50 value of 0.19 μg/ml, coxsackie B3 (CB3) virus with IC50 values of 0.33 μg/ml, coxsackie B4 (CB4) virus with IC50 values of 0.40 μg/ml, and enterovirus 71 (EV71) virus with IC50 values of less than 0.1 μg/ml. However, the compound did not possess antiviral activity against influenza A (Flu A/PR, Flu A/WS, H1N1) and B viruses at four concentrations ranging from 0.1 to 100 μg/ml. | - |
dc.publisher | Elsevier | - |
dc.title | Antiviral activity of raoulic acid from Raoulia australis against Picornaviruses | - |
dc.title.alternative | Antiviral activity of raoulic acid from Raoulia australis against Picornaviruses | - |
dc.type | Article | - |
dc.citation.title | Phytomedicine | - |
dc.citation.number | 1 | - |
dc.citation.endPage | 39 | - |
dc.citation.startPage | 35 | - |
dc.citation.volume | 16 | - |
dc.contributor.affiliatedAuthor | Hwa-Jung Choi | - |
dc.contributor.affiliatedAuthor | Dur Han Kwon | - |
dc.contributor.alternativeName | 최화정 | - |
dc.contributor.alternativeName | 임치환 | - |
dc.contributor.alternativeName | 송재형 | - |
dc.contributor.alternativeName | 백승화 | - |
dc.contributor.alternativeName | 권두한 | - |
dc.identifier.bibliographicCitation | Phytomedicine, vol. 16, no. 1, pp. 35-39 | - |
dc.identifier.doi | 10.1016/j.phymed.2008.10.012 | - |
dc.subject.keyword | Antiviral activity | - |
dc.subject.keyword | Raoulia australis | - |
dc.subject.keyword | Raoulic acid | - |
dc.subject.local | Antiviral activity | - |
dc.subject.local | antiviral activity | - |
dc.subject.local | Raoulia australis | - |
dc.subject.local | raoulic acid | - |
dc.subject.local | Raoulic acid | - |
dc.description.journalClass | Y | - |
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