Synthesis and biological evaluation of decursin, prantschimgin and their derivatives
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Y Xia | - |
| dc.contributor.author | K H Min | - |
| dc.contributor.author | Kyeong Lee | - |
| dc.date.accessioned | 2017-04-19T09:13:12Z | - |
| dc.date.available | 2017-04-19T09:13:12Z | - |
| dc.date.issued | 2009 | - |
| dc.identifier.issn | 0253-2964 | - |
| dc.identifier.uri | 10.5012/bkcs.2009.30.1.043 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/8829 | - |
| dc.description.abstract | The synthesis of coumarin-based natural products and their derivatives is described. In vitro MDR reversal activities of the synthesized compounds were evaluated in P-glycoprotein over-expressing human sarcoma cell line MES-SA/DX5. Some of the coumarin derivatives were found to show potent MDR reversal activity. In particular, pyridyl derivative (15e) exhibited more potency than verapamil. | - |
| dc.publisher | Wiley | - |
| dc.title | Synthesis and biological evaluation of decursin, prantschimgin and their derivatives | - |
| dc.title.alternative | Synthesis and biological evaluation of decursin, prantschimgin and their derivatives | - |
| dc.type | Article | - |
| dc.citation.title | Bulletin of Korean Chemical Society | - |
| dc.citation.number | 1 | - |
| dc.citation.endPage | 48 | - |
| dc.citation.startPage | 43 | - |
| dc.citation.volume | 30 | - |
| dc.contributor.affiliatedAuthor | Kyeong Lee | - |
| dc.contributor.alternativeName | Xia | - |
| dc.contributor.alternativeName | 민경훈 | - |
| dc.contributor.alternativeName | 이경 | - |
| dc.identifier.bibliographicCitation | Bulletin of Korean Chemical Society, vol. 30, no. 1, pp. 43-48 | - |
| dc.identifier.doi | 10.5012/bkcs.2009.30.1.043 | - |
| dc.subject.keyword | coumarins | - |
| dc.subject.keyword | decursin | - |
| dc.subject.keyword | multidrug resistance | - |
| dc.subject.keyword | P-glycoprotein | - |
| dc.subject.keyword | prantschimgin | - |
| dc.subject.local | coumarin | - |
| dc.subject.local | coumarins | - |
| dc.subject.local | Coumarins | - |
| dc.subject.local | Coumarin | - |
| dc.subject.local | Decursin | - |
| dc.subject.local | decursin | - |
| dc.subject.local | multidrug resistance | - |
| dc.subject.local | multidrug-resistance (MDR) | - |
| dc.subject.local | Multidrug resistance | - |
| dc.subject.local | Multidrug-resistance | - |
| dc.subject.local | P-glycoprotein | - |
| dc.subject.local | prantschimgin | - |
| dc.description.journalClass | Y | - |
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