DC Field | Value | Language |
---|---|---|
dc.contributor.author | H M KIm | - |
dc.contributor.author | S M Jin | - |
dc.contributor.author | S K Lee | - |
dc.contributor.author | Min-Gon Kim | - |
dc.contributor.author | Yong Beom Shin | - |
dc.date.accessioned | 2017-04-19T09:13:30Z | - |
dc.date.available | 2017-04-19T09:13:30Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1424-8220 | - |
dc.identifier.uri | 10.3390/s90402334 | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/8887 | - |
dc.description.abstract | To amplify the difference in localized surface plasmon resonance (LSPR) spectra of gold nano-islands due to intermolecular binding events, gold nanoparticles were used. LSPR-based optical biosensors consisting of gold nano-islands were readily made on glass substrates using evaporation and heat treatment. Streptavidin (STA) and biotinylated bovine serum albumin (Bio-BSA) were chosen as the model receptor and the model analyte, respectively, to demonstrate the effectiveness of this detection method. Using this model system, we were able to enhance the sensitivity in monitoring the binding of Bio- BSA to gold nano-island surfaces functionalized with STA through the addition of gold nanoparticle-STA conjugates. In addition, SU-8 well chips with gold nano-island surfaces were fabricated through a conventional UV patterning method and were then utilized for image detection using the attenuated total reflection mode. These results suggest that the gold nano-island well chip may have the potential to be used for multiple and simultaneous detection of various bio-substances. | - |
dc.publisher | MDPI | - |
dc.title | Detection of biomolecular binding through enhancement of localized surface plasmon resonance (LSPR) by gold nanoparticles | - |
dc.title.alternative | Detection of biomolecular binding through enhancement of localized surface plasmon resonance (LSPR) by gold nanoparticles | - |
dc.type | Article | - |
dc.citation.title | Sensors | - |
dc.citation.number | 4 | - |
dc.citation.endPage | 2344 | - |
dc.citation.startPage | 2334 | - |
dc.citation.volume | 9 | - |
dc.contributor.affiliatedAuthor | Min-Gon Kim | - |
dc.contributor.affiliatedAuthor | Yong Beom Shin | - |
dc.contributor.alternativeName | 김형민 | - |
dc.contributor.alternativeName | 진승민 | - |
dc.contributor.alternativeName | 이석기 | - |
dc.contributor.alternativeName | 김민곤 | - |
dc.contributor.alternativeName | 신용범 | - |
dc.identifier.bibliographicCitation | Sensors, vol. 9, no. 4, pp. 2334-2344 | - |
dc.identifier.doi | 10.3390/s90402334 | - |
dc.subject.keyword | attenuated total reflection (ATR) | - |
dc.subject.keyword | gold nano-island | - |
dc.subject.keyword | gold nanoparticle | - |
dc.subject.keyword | localized surface plasmon resonance (LSPR) | - |
dc.subject.keyword | well chip | - |
dc.subject.local | attenuated total reflection (ATR) | - |
dc.subject.local | Attenuated total reflection | - |
dc.subject.local | Gold nano-island | - |
dc.subject.local | gold nano-island | - |
dc.subject.local | gold nanoparticle | - |
dc.subject.local | Gold nanoparticles | - |
dc.subject.local | Gold nanoparticle (AuNP) | - |
dc.subject.local | Gold nanoparticle | - |
dc.subject.local | localized surface plasmon resonance | - |
dc.subject.local | Localized surface plasmon resonance (LSPR) | - |
dc.subject.local | Localized surface plasmon resonance | - |
dc.subject.local | localized surface plasmon resonance (LSPR) | - |
dc.subject.local | Well chip | - |
dc.subject.local | well chip | - |
dc.description.journalClass | Y | - |
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