Detection of biomolecular binding through enhancement of localized surface plasmon resonance (LSPR) by gold nanoparticles

Cited 50 time in scopus
Metadata Downloads

Full metadata record

DC FieldValueLanguage
dc.contributor.authorH M KIm-
dc.contributor.authorS M Jin-
dc.contributor.authorS K Lee-
dc.contributor.authorMin-Gon Kim-
dc.contributor.authorYong Beom Shin-
dc.date.accessioned2017-04-19T09:13:30Z-
dc.date.available2017-04-19T09:13:30Z-
dc.date.issued2009-
dc.identifier.issn1424-8220-
dc.identifier.uri10.3390/s90402334ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/8887-
dc.description.abstractTo amplify the difference in localized surface plasmon resonance (LSPR) spectra of gold nano-islands due to intermolecular binding events, gold nanoparticles were used. LSPR-based optical biosensors consisting of gold nano-islands were readily made on glass substrates using evaporation and heat treatment. Streptavidin (STA) and biotinylated bovine serum albumin (Bio-BSA) were chosen as the model receptor and the model analyte, respectively, to demonstrate the effectiveness of this detection method. Using this model system, we were able to enhance the sensitivity in monitoring the binding of Bio- BSA to gold nano-island surfaces functionalized with STA through the addition of gold nanoparticle-STA conjugates. In addition, SU-8 well chips with gold nano-island surfaces were fabricated through a conventional UV patterning method and were then utilized for image detection using the attenuated total reflection mode. These results suggest that the gold nano-island well chip may have the potential to be used for multiple and simultaneous detection of various bio-substances.-
dc.publisherMDPI-
dc.titleDetection of biomolecular binding through enhancement of localized surface plasmon resonance (LSPR) by gold nanoparticles-
dc.title.alternativeDetection of biomolecular binding through enhancement of localized surface plasmon resonance (LSPR) by gold nanoparticles-
dc.typeArticle-
dc.citation.titleSensors-
dc.citation.number4-
dc.citation.endPage2344-
dc.citation.startPage2334-
dc.citation.volume9-
dc.contributor.affiliatedAuthorMin-Gon Kim-
dc.contributor.affiliatedAuthorYong Beom Shin-
dc.contributor.alternativeName김형민-
dc.contributor.alternativeName진승민-
dc.contributor.alternativeName이석기-
dc.contributor.alternativeName김민곤-
dc.contributor.alternativeName신용범-
dc.identifier.bibliographicCitationSensors, vol. 9, no. 4, pp. 2334-2344-
dc.identifier.doi10.3390/s90402334-
dc.subject.keywordattenuated total reflection (ATR)-
dc.subject.keywordgold nano-island-
dc.subject.keywordgold nanoparticle-
dc.subject.keywordlocalized surface plasmon resonance (LSPR)-
dc.subject.keywordwell chip-
dc.subject.localattenuated total reflection (ATR)-
dc.subject.localAttenuated total reflection-
dc.subject.localGold nano-island-
dc.subject.localgold nano-island-
dc.subject.localgold nanoparticle-
dc.subject.localGold nanoparticles-
dc.subject.localGold nanoparticle (AuNP)-
dc.subject.localGold nanoparticle-
dc.subject.locallocalized surface plasmon resonance-
dc.subject.localLocalized surface plasmon resonance (LSPR)-
dc.subject.localLocalized surface plasmon resonance-
dc.subject.locallocalized surface plasmon resonance (LSPR)-
dc.subject.localWell chip-
dc.subject.localwell chip-
dc.description.journalClassY-
Appears in Collections:
Division of Research on National Challenges > Bionanotechnology Research Center > 1. Journal Articles
Files in This Item:

Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.