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- Title
- Aspochalasin I, a melanogenesis inhibitor from Aspergillus sp.
- Author(s)
- Soo-Jin Choo; B S Yun; In Ja Ryoo; Young Hee Kim; K H Bae; Ick Dong Yoo
- Bibliographic Citation
- Journal of Microbiology and Biotechnology, vol. 19, no. 4, pp. 368-371
- Publication Year
- 2009
- Abstract
- In the course of screening for the melanogenesis inhibitors, aspochalasin I was isolated from solid-state culture of Aspergillus sp. Fb020460. Its structure was determined by spectroscopic analysis including mass spectroscopy and NMR analysis. Aspochalasin I potently inhibited melanogenesis in Mel-Ab cells with an IC50 value of 22.4 muM without cytotoxicity.
- Keyword
- Melanogenesisaspochalasin IAspergillus sp.
- ISSN
- 1017-7825
- Publisher
- Korea Soc-Assoc-Inst
- DOI
- http://dx.doi.org/10.4014/jmb.0806.389
- Type
- Article
- Appears in Collections:
- Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
- Files in This Item:
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