Aspochalasin I, a melanogenesis inhibitor from Aspergillus sp.

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Title
Aspochalasin I, a melanogenesis inhibitor from Aspergillus sp.
Author(s)
Soo-Jin Choo; B S Yun; In Ja Ryoo; Young Hee Kim; K H Bae; Ick Dong Yoo
Bibliographic Citation
Journal of Microbiology and Biotechnology, vol. 19, no. 4, pp. 368-371
Publication Year
2009
Abstract
In the course of screening for the melanogenesis inhibitors, aspochalasin I was isolated from solid-state culture of Aspergillus sp. Fb020460. Its structure was determined by spectroscopic analysis including mass spectroscopy and NMR analysis. Aspochalasin I potently inhibited melanogenesis in Mel-Ab cells with an IC50 value of 22.4 muM without cytotoxicity.
Keyword
Melanogenesisaspochalasin IAspergillus sp.
ISSN
1017-7825
Publisher
Korea Soc-Assoc-Inst
DOI
http://dx.doi.org/10.4014/jmb.0806.389
Type
Article
Appears in Collections:
Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
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