Farnesyl protein transferase inhibitory components of Polygonum multiflorum
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Byoung-Mog Kwon | - |
| dc.contributor.author | S H Kim | - |
| dc.contributor.author | N I Baek | - |
| dc.contributor.author | S I Lee | - |
| dc.contributor.author | E J Kim | - |
| dc.contributor.author | J H Yang | - |
| dc.contributor.author | B S Chae | - |
| dc.contributor.author | J H Lee | - |
| dc.contributor.author | H W Park | - |
| dc.contributor.author | J S Park | - |
| dc.contributor.author | D K Kim | - |
| dc.date.accessioned | 2017-04-19T09:13:40Z | - |
| dc.date.available | 2017-04-19T09:13:40Z | - |
| dc.date.issued | 2009 | - |
| dc.identifier.issn | 0253-6269 | - |
| dc.identifier.uri | 10.1007/s12272-009-1403-y | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/8924 | - |
| dc.description.abstract | The methanolic extract of the roots of Polygonum multiflorum (Polygonaceae) was found to show inhibitory activity towards farnesyl protein transferase (FPTase). Bioassay-guided fractionation of the methanolic extract resulted in the isolation of two anthraquinone glycosides, as inhibitors of FPTase. These compounds inhibited the FPTase activity in a dose-dependent manner. | - |
| dc.publisher | Pharmaceutical Soc Korea | - |
| dc.title | Farnesyl protein transferase inhibitory components of Polygonum multiflorum | - |
| dc.title.alternative | Farnesyl protein transferase inhibitory components of Polygonum multiflorum | - |
| dc.type | Article | - |
| dc.citation.title | Archives of Pharmacal Research | - |
| dc.citation.number | 4 | - |
| dc.citation.endPage | 499 | - |
| dc.citation.startPage | 495 | - |
| dc.citation.volume | 32 | - |
| dc.contributor.affiliatedAuthor | Byoung-Mog Kwon | - |
| dc.contributor.alternativeName | 권병목 | - |
| dc.contributor.alternativeName | 김성훈 | - |
| dc.contributor.alternativeName | 백남인 | - |
| dc.contributor.alternativeName | 이사임 | - |
| dc.contributor.alternativeName | 김은정 | - |
| dc.contributor.alternativeName | 양재헌 | - |
| dc.contributor.alternativeName | 채병석 | - |
| dc.contributor.alternativeName | 이재혁 | - |
| dc.contributor.alternativeName | 박희욱 | - |
| dc.contributor.alternativeName | 박정숙 | - |
| dc.contributor.alternativeName | 김대근 | - |
| dc.identifier.bibliographicCitation | Archives of Pharmacal Research, vol. 32, no. 4, pp. 495-499 | - |
| dc.identifier.doi | 10.1007/s12272-009-1403-y | - |
| dc.subject.keyword | anthraquinone glycosides | - |
| dc.subject.keyword | FPTase | - |
| dc.subject.keyword | polygonaceae | - |
| dc.subject.keyword | polygonum multiflorum | - |
| dc.subject.local | anthraquinone glycosides | - |
| dc.subject.local | FPTase | - |
| dc.subject.local | polygonaceae | - |
| dc.subject.local | polygonum multiflorum | - |
| dc.subject.local | Polygonum multiflorum | - |
| dc.description.journalClass | Y | - |
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