Phenolic glycosides from Alangium salviifolium leaves with inhibitory activity on LPS-induced NO, PGE2, and TNF-α production

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dc.contributor.authorT M Hung-
dc.contributor.authorN H Dang-
dc.contributor.authorJ C Kim-
dc.contributor.authorJ S Choi-
dc.contributor.authorHyeong Kyu Lee-
dc.contributor.authorB S Min-
dc.date.accessioned2017-04-19T09:14:08Z-
dc.date.available2017-04-19T09:14:08Z-
dc.date.issued2009-
dc.identifier.issn0960-894X-
dc.identifier.uri10.1016/j.bmcl.2009.05.070ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/9045-
dc.description.abstractThree new phenolic glycosides, salviifosides A-C (1-3), and three known compounds salicin (4), kaempferol (5), and kaempferol 3-O-β-D-glucopyranoside (6) were isolated from the leaves of Alangium salviifolium (L.f.) Wangerin (Alangiaceae). The structures of the new metabolites were determined on the basic of spectroscopic analyses including two dimensional NMR. The anti-inflammatory activities of new compounds (1-3) were investigated on lipopolysaccharide (LPS)-induced murine macrophage cells line, RAW 264.7. Salviifoside B (2) potentially inhibits the productions of nitric oxide (NO), prostaglandin E2 (PGE2), and tumor necrosis factor-a (TNF-α).-
dc.publisherElsevier-
dc.titlePhenolic glycosides from Alangium salviifolium leaves with inhibitory activity on LPS-induced NO, PGE2, and TNF-α production-
dc.title.alternativePhenolic glycosides from Alangium salviifolium leaves with inhibitory activity on LPS-induced NO, PGE2, and TNF-α production-
dc.typeArticle-
dc.citation.titleBioorganic & Medicinal Chemistry Letters-
dc.citation.number15-
dc.citation.endPage4393-
dc.citation.startPage4389-
dc.citation.volume19-
dc.contributor.affiliatedAuthorHyeong Kyu Lee-
dc.contributor.alternativeNameHung-
dc.contributor.alternativeNameDang-
dc.contributor.alternativeName김진철-
dc.contributor.alternativeName최재수-
dc.contributor.alternativeName이형규-
dc.contributor.alternativeName민병선-
dc.identifier.bibliographicCitationBioorganic & Medicinal Chemistry Letters, vol. 19, no. 15, pp. 4389-4393-
dc.identifier.doi10.1016/j.bmcl.2009.05.070-
dc.subject.keywordAlangium salviifolium-
dc.subject.keywordAlangiaceae-
dc.subject.keywordPhenolic glycosides-
dc.subject.keywordAnti-inflammatory-
dc.subject.localAlangium salviifolium-
dc.subject.localAlangiaceae-
dc.subject.localPhenolic glycosides-
dc.subject.localphenolic glycosides-
dc.subject.localanti-inflammatory-
dc.subject.localAnti-inflammatory-
dc.description.journalClassY-
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