Fingerprinting differentiation of Astragalus membranaceus roots according to ages using 1H-NMR spectroscopy and multivariate statistical analysis

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dc.contributor.authorY S Shin-
dc.contributor.authorK H Bang-
dc.contributor.authorD S In-
dc.contributor.authorJ S Sung-
dc.contributor.authorS Y Kim-
dc.contributor.authorB C Ku-
dc.contributor.authorSuk Weon Kim-
dc.contributor.authorD Lee-
dc.contributor.authorH K Choi-
dc.date.accessioned2017-04-19T09:14:34Z-
dc.date.available2017-04-19T09:14:34Z-
dc.date.issued2009-
dc.identifier.issn1976-9148-
dc.identifier.uri10.4062/biomolther.2009.17.2.133ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/9109-
dc.description.abstractThe root of Astragalus membranaceus is a traditional folk medicine that has been used for many therapeutic purposes in Asia. It reportedly acts as an immunostimulant, tonic, hepatoprotective, diuretic, antidiabetic, analgesic, expectorant, sedative, and anticancer drug. In this study, metabolomic profiling was applied to the roots of A. membranaceus of different ages using NMR coupled with two multivariate statistical analysis methods: such as principal components analysis (PCA) and canonical discriminant analysis (CDA). This allowed various metabolites to be assigned in NMR spectra, including γ-aminobutyric acid (GABA), aspartic acid, succinic acid, glutamic acid, glutamine, N-acetyl aspartic acid, acetic acid, arginine, alanine, threonine, lactic acid, and valine. The score plot from PCA and also CDA allowed a clear separation between samples according to age.-
dc.publisherKorea Soc-Assoc-Inst-
dc.titleFingerprinting differentiation of Astragalus membranaceus roots according to ages using 1H-NMR spectroscopy and multivariate statistical analysis-
dc.title.alternativeFingerprinting differentiation of Astragalus membranaceus roots according to ages using 1H-NMR spectroscopy and multivariate statistical analysis-
dc.typeArticle-
dc.citation.titleBiomolecules & Therapeutics-
dc.citation.number2-
dc.citation.endPage137-
dc.citation.startPage133-
dc.citation.volume17-
dc.contributor.affiliatedAuthorSuk Weon Kim-
dc.contributor.alternativeName신유수-
dc.contributor.alternativeName방경환-
dc.contributor.alternativeName인동수-
dc.contributor.alternativeName성정숙-
dc.contributor.alternativeName김선영-
dc.contributor.alternativeName구본초-
dc.contributor.alternativeName김석원-
dc.contributor.alternativeName이동호-
dc.contributor.alternativeName최형균-
dc.identifier.bibliographicCitationBiomolecules & Therapeutics, vol. 17, no. 2, pp. 133-137-
dc.identifier.doi10.4062/biomolther.2009.17.2.133-
dc.subject.keyword1H NMR spectroscopy-
dc.subject.keywordAstragalus membranaceus-
dc.subject.keywordCanonical discriminant analysis-
dc.subject.keywordFingerprinting analysis-
dc.subject.keywordPrincipal component analysis-
dc.subject.local1H-NMR spectroscopy-
dc.subject.local1H NMR spectroscopy-
dc.subject.localAstragalus membranaceus-
dc.subject.localCanonical discriminant analysis-
dc.subject.localFingerprinting analysis-
dc.subject.localprincipal component analysis (PCA)-
dc.subject.localPrincipal Component Analysis-
dc.subject.localPrincipal component analysis (PCA)-
dc.subject.localprincipal component analysis-
dc.subject.localprincipal components analysis-
dc.subject.localPrincipal component analysis-
dc.description.journalClassY-
Appears in Collections:
Jeonbuk Branch Institute > Biological Resource Center > 1. Journal Articles
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