A highly selective fluorescent ESIPT probe for the dual specificity phosphatase MKP-6 = 이중선택성 탈인산화효소 MKP-6에 선택적인 형광 ESIPT 탐침 개발

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Title
A highly selective fluorescent ESIPT probe for the dual specificity phosphatase MKP-6 = 이중선택성 탈인산화효소 MKP-6에 선택적인 형광 ESIPT 탐침 개발
Author(s)
T I Kim; Hyo Jin Kang; G Han; Sang Jeon Chung; Y Kim
Bibliographic Citation
Chemical Communications, vol. 2009, no. 39, pp. 5895-5897
Publication Year
2009
Abstract
A highly selective fluorescent probe for a protein tyrosine phosphatase (PTP) was designed by a simple phosphorylation of the 2-(2′-hydroxyphenyl) benzothiazole (HBT) chromophore: upon selective enzymatic hydrolysis, an excited-state intramolecular proton transfer (ESIPT) occurs, resulting in a large Stokes shift.
ISSN
1359-7345
Publisher
Royal Soc Chem
DOI
http://dx.doi.org/10.1039/b911145j
Type
Article
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1. Journal Articles > Journal Articles
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