DC Field | Value | Language |
---|---|---|
dc.contributor.author | P M Giang | - |
dc.contributor.author | P T Son | - |
dc.contributor.author | H Z Jin | - |
dc.contributor.author | J H Lee | - |
dc.contributor.author | Jung Joon Lee | - |
dc.date.accessioned | 2017-04-19T09:15:11Z | - |
dc.date.available | 2017-04-19T09:15:11Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0036-8709 | - |
dc.identifier.uri | 10.3797/scipharm.0907-16 | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/9186 | - |
dc.description.abstract | In the present study the significant role of the α,β-unsaturated carbonyl structure in the anti-inflammatory activity of the natural humulane sesquiterpenoids zerumbone and zerumbone 2,3-epoxide was evidenced from a comparative study of the ability of zerumbone and zerumbone 2,3-epoxide to inhibit NF-κB activation and NO production in LPS (lipopolysaccharide)- stimulated RAW 264.7 cells. The IC50 of these compounds were 1.97 μM ± 0.18 and 30.11 μM ± 4.10 in the NF-κB activation assay and 3.58 μM ± 0.46 and 34.7 μM ± 3.72 in the nitric oxide production assay, respectively. | - |
dc.publisher | ?sterreichischer Apothekerverlag | ko |
dc.title | Comparative study on inhibitory activity of zerumbone and zerumbone 2,3-epoxide on NF-κB activation and NO production | - |
dc.title.alternative | Comparative study on inhibitory activity of zerumbone and zerumbone 2,3-epoxide on NF-κB activation and NO production | - |
dc.type | Article | - |
dc.citation.title | Scientia Pharmaceutica | - |
dc.citation.number | 3 | - |
dc.citation.endPage | 595 | - |
dc.citation.startPage | 589 | - |
dc.citation.volume | 77 | - |
dc.contributor.affiliatedAuthor | Jung Joon Lee | - |
dc.contributor.alternativeName | Giang | - |
dc.contributor.alternativeName | Son | - |
dc.contributor.alternativeName | Jin | - |
dc.contributor.alternativeName | 이정형 | - |
dc.contributor.alternativeName | 이정준 | - |
dc.identifier.bibliographicCitation | Scientia Pharmaceutica, vol. 77, no. 3, pp. 589-595 | - |
dc.identifier.doi | 10.3797/scipharm.0907-16 | - |
dc.subject.keyword | NF-κB | - |
dc.subject.keyword | NO production | - |
dc.subject.keyword | Zerumbone | - |
dc.subject.keyword | Zerumbone-2,3-epoxide | - |
dc.subject.local | Nuclear factor-kappa B | - |
dc.subject.local | nuclear factor κB | - |
dc.subject.local | Nf-κb | - |
dc.subject.local | NF-kB | - |
dc.subject.local | nuclear factor kappa B | - |
dc.subject.local | NF-κB (nuclear factor kappa-B) | - |
dc.subject.local | NF-kappaB | - |
dc.subject.local | Nuclear factor-κb | - |
dc.subject.local | NF-κ B | - |
dc.subject.local | NF-κB | - |
dc.subject.local | NF-kappa B | - |
dc.subject.local | Nuclear factor κB (NF-κB) | - |
dc.subject.local | Nuclear factor κB | - |
dc.subject.local | NFκB | - |
dc.subject.local | Nf-κB | - |
dc.subject.local | Nuclear factor-κB | - |
dc.subject.local | nuclear factorκB | - |
dc.subject.local | Nuclear factor (NF)-κB | - |
dc.subject.local | Nuclear factor kappa B | - |
dc.subject.local | nuclear factor-κB | - |
dc.subject.local | NF-ΚB | - |
dc.subject.local | Nuclear factor-kappa B (NF-κB) | - |
dc.subject.local | Nuclear factor-kappaB | - |
dc.subject.local | nuclear factor-kappaB | - |
dc.subject.local | nuclear factor-kappaB (NF-κB) | - |
dc.subject.local | NFkappaB | - |
dc.subject.local | Nuclear factor kappaB | - |
dc.subject.local | NO production | - |
dc.subject.local | Zerumbone | - |
dc.subject.local | Zerumbone-2,3-epoxide | - |
dc.description.journalClass | N | - |
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