Improved ethanol tolerance in Escherichia coli by changing the cellular fatty acids composition through genetic manipulation = 세포막지방산 조성의 제어를 통한 에탄올 내성 증진

Cited 38 time in scopus
Metadata Downloads

Full metadata record

DC FieldValueLanguage
dc.contributor.authorL H Luo-
dc.contributor.authorPil-Soo Seo-
dc.contributor.authorJeong Woo Seo-
dc.contributor.authorSun Yeon Heo-
dc.contributor.authorD H Kim-
dc.contributor.authorChul Ho Kim-
dc.date.accessioned2017-04-19T09:15:22Z-
dc.date.available2017-04-19T09:15:22Z-
dc.date.issued2009-
dc.identifier.issn01415492-
dc.identifier.uri10.1007/s10529-009-0092-4ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/9192-
dc.description.abstractTo investigate the effect of cellular fatty acids composition on ethanol tolerance in Escherichia coli, we overexpressed either des, encoding fatty acid desaturase from Bacillus subtilis, or fabA, encoding β-hydroxydecanoyl thio-ester dehydrase from E. coli, or both genes together, into E. coli. Recombinant E. coli harboring fabA had elevated tolerance against ethanol compared to wild type strain. In contrast, des decreased resistance to ethanol. Co-expression of both genes together complemented ethanol tolerance of E. coli. This result indicates how to engineer bacterial strains to be resistant to higher concentrations of ethanol.-
dc.publisherSpringer-
dc.titleImproved ethanol tolerance in Escherichia coli by changing the cellular fatty acids composition through genetic manipulation = 세포막지방산 조성의 제어를 통한 에탄올 내성 증진-
dc.title.alternativeImproved ethanol tolerance in Escherichia coli by changing the cellular fatty acids composition through genetic manipulation-
dc.typeArticle-
dc.citation.titleBiotechnology Letters-
dc.citation.number12-
dc.citation.endPage1871-
dc.citation.startPage1867-
dc.citation.volume31-
dc.contributor.affiliatedAuthorJeong Woo Seo-
dc.contributor.affiliatedAuthorSun Yeon Heo-
dc.contributor.affiliatedAuthorChul Ho Kim-
dc.contributor.alternativeNameLuo-
dc.contributor.alternativeName서필수-
dc.contributor.alternativeName서정우-
dc.contributor.alternativeName허선연-
dc.contributor.alternativeName김대혁-
dc.contributor.alternativeName김철호-
dc.identifier.bibliographicCitationBiotechnology Letters, vol. 31, no. 12, pp. 1867-1871-
dc.identifier.doi10.1007/s10529-009-0092-4-
dc.subject.keywordDesaturase-
dc.subject.keywordEscherichia coli-
dc.subject.keywordEthanol tolerance-
dc.subject.keywordFabA-
dc.subject.keywordFatty acids composition-
dc.subject.localDesaturase-
dc.subject.localEscherichia coli-
dc.subject.localEthanol tolerance-
dc.subject.localFabA-
dc.subject.localFatty acids composition-
dc.description.journalClassY-
Appears in Collections:
Jeonbuk Branch Institute > Microbial Biotechnology Research Center > 1. Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.