Reticulone, a novel free radical scavenger produced by Aspergillus sp.

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Title
Reticulone, a novel free radical scavenger produced by Aspergillus sp.
Author(s)
In Ja Ryoo; G H Xu; Young-hee Kim; Soo-Jin Choo; Jong Seog Ahn; K Bae; Ick Dong Yoo
Bibliographic Citation
Journal of Microbiology and Biotechnology, vol. 19, no. 12, pp. 1573-1575
Publication Year
2009
Abstract
Bioassay-guided fractionation of the culture broth of Aspergillus sp. FN070449 (KCTC 26428) using a DPPH (2,2-diphenyl-1-picrylhydrazyl) assay led to the isolation of two compounds: reticulone (1) and reticulol (2). Their chemical structures were elucidated on the basis of UV, IR, NMR, and MS spectroscopic analyses. Compound 1 exhibited more potent free radical scavenging activity on ABTS?+ (2,2′-azino-bis [3-ethylbenzthiazoline-6-sulphonic acid]) and DPPH radicals than did butylated hydroxyanisole (BHA) and caffeic acid.
Keyword
ABTSAspergillus sp.DPPHReticulone
ISSN
1017-7825
Publisher
South Korea
DOI
http://dx.doi.org/10.4014/jmb.0906.06033
Type
Article
Appears in Collections:
Ochang Branch Institute > Anticancer Agent Research Center > 1. Journal Articles
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