CONVIRT: a web-based tool for transcriptional regulatory site identification using a conserved virtual chromosome

Cited 0 time in scopus
Metadata Downloads
Title
CONVIRT: a web-based tool for transcriptional regulatory site identification using a conserved virtual chromosome
Author(s)
Taewoo Ryu; S Lee; Cheol-Goo Hur; D Lee
Bibliographic Citation
BMB Reports, vol. 42, no. 12, pp. 823-828
Publication Year
2009
Abstract
Techniques for analyzing protein-DNA interactions on a genome-wide scale have recently established regulatory roles for distal enhancers. However, the large sizes of higher eukaryotic genomes have made identification of these elements difficult. Information regarding sequence conservation, exon annotation and repetitive regions can be used to reduce the size of the search region. However, previously developed resources are inadequate for consolidating such information. CONVIRT is a web resource for the identification of transcription factor binding sites and also features comparative genomics. Genomic information on ortholog-independent conserved regions, exons, repeats and sequences is integrated into the virtual chromosome, and statistically over-represented single or combinations of transcription factor binding sites are sought. CONVIRT provides regulatory network analysis for several organisms with long promoter regions and permits inter-species genome alignments. CONVIRT is freely available at http://biosoft.kaist. ac.kr/convirt.
Keyword
Cis-elementComparative genomicsPhylogenetic footprintingTFBSTranscription factor
ISSN
1225-8687
Publisher
South Korea
DOI
http://dx.doi.org/10.5483/BMBRep.2009.42.12.823
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.