Application as a cosmeceutical ingredient of Euryale ferox seed extract = 가시연꽃 종자 추출물의 화장품 원료로서의 특성

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Title
Application as a cosmeceutical ingredient of Euryale ferox seed extract = 가시연꽃 종자 추출물의 화장품 원료로서의 특성
Author(s)
Soo-Jin Choo; Y H Kim; In Ja Ryoo; G H Xu; Ick Dong Yoo
Bibliographic Citation
Journal of Society of Cosmetic Scientists of Korea (Old), vol. 35, no. 4, pp. 309-315
Publication Year
2009
Abstract
In our search for the natural cosmetic ingredients, we found that Euryale ferox seed extract exhibited the strong antioxidative activity. Five active compounds were isolated from the ethyl acetate extract through various chromatographic methods and their structures were determined by NMR and MS spectral analysis. These compounds were identified as fucosterol (1), 3-(4-hydroxy-3-methoxybenzyl)-4-[(7'R),5'-dihydroxy-3'-methoxybenzyl]tetrahydrofuran (2), resorcinol (3), pyrogallol (4) and 4-O-methylgallic acid (5).We evaluated the antioxidative, antielastase activities and melanogenesis inhibitory effects of these compounds. The values of compounds 2 ~ 5 for free radical scavenging activity were and especially compounds 4 and 5 were 6-fold more effective than ferulic acid as a positive control. And compounds 2 ~ 4 inhibited human neutrophil elastase with values of and compound 3 also inhibited melanin synthesis in B16F10 melanoma cells with an value of . These results suggest that Euryale ferox extract having a lot of various active ingredients may be useful as a natural multi-functioning agent.
Keyword
Euryale feroxantioxidativeantielastasemelanogenesiselastase inhibition
ISSN
I000-0160
Publisher
South Korea
Type
Article
Appears in Collections:
Ochang Branch Institute > Anticancer Agent Research Center > 1. Journal Articles
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