Open Access@KRIBBDivision of Research on National ChallengesInfectious Disease Research Center1. Journal Articles
Isolation and identification of FR198248, a hydroxylated 1,4-dihydroisobenzofuran, from Aspergillus flavipes F543 as an inhibitor of peptide deformylase = Aspergillus flavipes균주로 부터 PDF 저해제 FR198248의 분리 및 동정
Cited 23 time in 
Metadata Downloads
Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Yun-Ju Kwon | - |
| dc.contributor.author | C J Zheng | - |
| dc.contributor.author | Won Gon Kim | - |
| dc.date.accessioned | 2017-04-19T09:17:28Z | - |
| dc.date.available | 2017-04-19T09:17:28Z | - |
| dc.date.issued | 2010 | - |
| dc.identifier.issn | 0916-8451 | - |
| dc.identifier.uri | 10.1271/bbb.90565 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/9421 | - |
| dc.description.abstract | Two highly hydroxylated 1,3-dihydroisobenzofurans, FR198248 (1) and FR202306 (2), were isolated as peptide deformylase (PDF) inhibitors from Aspergillus flavipes. Compounds 1 and 2 inhibited Staphylococus aureus PDF with IC50 values of 3.6 and 2.5 μM, respectively, and also showed antibacterial activity with an MIC value of 25 μg/ml. In contrast, 6-O-methyl derivative 3 of compound 2 was inactive against both PDF and S. aureus. | - |
| dc.publisher | T&F (Taylor & Francis) | - |
| dc.title | Isolation and identification of FR198248, a hydroxylated 1,4-dihydroisobenzofuran, from Aspergillus flavipes F543 as an inhibitor of peptide deformylase = Aspergillus flavipes균주로 부터 PDF 저해제 FR198248의 분리 및 동정 | - |
| dc.title.alternative | Isolation and identification of FR198248, a hydroxylated 1,4-dihydroisobenzofuran, from Aspergillus flavipes F543 as an inhibitor of peptide deformylase | - |
| dc.type | Article | - |
| dc.citation.title | Bioscience Biotechnology and Biochemistry | - |
| dc.citation.number | 2 | - |
| dc.citation.endPage | 393 | - |
| dc.citation.startPage | 390 | - |
| dc.citation.volume | 74 | - |
| dc.contributor.affiliatedAuthor | Yun-Ju Kwon | - |
| dc.contributor.affiliatedAuthor | Won Gon Kim | - |
| dc.contributor.alternativeName | 권윤주 | - |
| dc.contributor.alternativeName | Zheng | - |
| dc.contributor.alternativeName | 김원곤 | - |
| dc.identifier.bibliographicCitation | Bioscience Biotechnology and Biochemistry, vol. 74, no. 2, pp. 390-393 | - |
| dc.identifier.doi | 10.1271/bbb.90565 | - |
| dc.subject.keyword | 1,3-dihydroisobenzofuran | - |
| dc.subject.keyword | Antibacterial | - |
| dc.subject.keyword | Aspergillus flavipes | - |
| dc.subject.keyword | Peptide deformylase | - |
| dc.subject.keyword | Staphylococcus aureus | - |
| dc.subject.local | 1,3-dihydroisobenzofuran | - |
| dc.subject.local | Antibacterial | - |
| dc.subject.local | Antibacterials | - |
| dc.subject.local | antibacterial | - |
| dc.subject.local | Anti-bacterial | - |
| dc.subject.local | antibacterials | - |
| dc.subject.local | Aspergillus flavipes | - |
| dc.subject.local | Peptide deformylase | - |
| dc.subject.local | Staphylococcus aureus | - |
| dc.subject.local | staphylococcus aureus | - |
| dc.description.journalClass | Y | - |
- Appears in Collections:
- Division of Research on National Challenges > Infectious Disease Research Center > 1. Journal Articles
- Files in This Item:
There are no files associated with this item.
Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.