Open Access@KRIBBDivision of A.I. & Biomedical ResearchMicrobiome Convergence Research Center1. Journal Articles
Triterpenoid and lignan from the fruits of Cornus kousa inhibit the activities of PRL-3 and LDL-oxidation
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- Title
- Triterpenoid and lignan from the fruits of Cornus kousa inhibit the activities of PRL-3 and LDL-oxidation
- Author(s)
- D Y Lee; M H Lee; Tae Sook Jeong; Byoung-Mog Kwon; N I Baek; Y D Rho
- Bibliographic Citation
- Journal of Korean Society for Applied Biological Chemistry, vol. 53, no. 1, pp. 97-100
- Publication Year
- 2010
- Abstract
- Ursolic aldehyde (1) and (+)-lariciresinol (2) were isolated from the MeOH extracted fraction of the fruits of Cornus kousa by repeated column chromatographies. The structure of the compounds were determined by spectroscopic data including nuclear magnetic resonance spectrometry, mass spectrometry and infrared spectrometry Ursolic aldehyde inhibited phosphatase of regenerating liver-3 with IC50 value of 50±0.3 μM. And (+)-lariciresinol inhibited low-density lipoprotein oxidation with an IC50 value of 11.9±0.5 μM.
- ISSN
- I000-0171
- Publisher
- Korea Soc-Assoc-Inst
- Full Text Link
- http://dx.doi.org/10.3839/jksabc.2010.016
- Type
- Article
- Appears in Collections:
- Division of A.I. & Biomedical Research > Microbiome Convergence Research Center > 1. Journal Articles
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