Two acetylated megastigmane glycosides from the leaves of Ilex paraguariensis

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Title
Two acetylated megastigmane glycosides from the leaves of Ilex paraguariensis
Author(s)
G H Xu; Y H Kim; Soo-Jin Choo; In Ja Ryoo; J K Yoo; Jong Seog Ahn; Ick Dong Yoo
Bibliographic Citation
Archives of Pharmacal Research, vol. 33, no. 3, pp. 369-373
Publication Year
2010
Abstract
Two acetylated megastigmane glycosides, matenosides A (1) and B (2), have been isolatedm from the MeOH extract of Ilex paraguariensis leaves, and their structures were elucidated on the basis of spectroscopic analysis. Compounds 1 and 2 exhibited human neutrophil elastase (HNE) inhibitory activity with IC50 values of 50.4 μM and 11.1 μM, respectively.
Keyword
Ilex paraguariensisMatenosides A and BMegastigmane glycosides
ISSN
0253-6269
Publisher
Pharmaceutical Soc Korea
DOI
http://dx.doi.org/10.1007/s12272-010-0304-4
Type
Article
Appears in Collections:
Ochang Branch Institute > Anticancer Agent Research Center > 1. Journal Articles
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