DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yong Taik Lim | - |
dc.contributor.author | M Y Cho | - |
dc.contributor.author | J H Kang | - |
dc.contributor.author | Y W Noh | - |
dc.contributor.author | J H Cho | - |
dc.contributor.author | K S Hong | - |
dc.contributor.author | J W Chung | - |
dc.contributor.author | Bong Hyun Chung | - |
dc.date.accessioned | 2017-04-19T09:18:21Z | - |
dc.date.available | 2017-04-19T09:18:21Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0142-9612 | - |
dc.identifier.uri | 10.1016/j.biomaterials.2010.02.065 | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/9489 | - |
dc.description.abstract | Multimodal imaging contrast agents with unique magnetic resonance (MR) and optical imaging capabilities have great potentials in the diagnosis and therapy of disease. Using a rational materials design approach, the bimodal imaging contrast agent, perfluorodecalin (PFD)/[InGaP/ZnS quantum dots (QDs)] composite nanoemulsions is developed in this study. 19F molecules in the PFD/[InGaP/ZnS QDs] nanoemulsions provide a 19F-based MR imaging capability, while fluorescent QDs dispersed in PFD nanodroplets provide an optical imaging modality. This study also demonstrates that these bimodal imaging contrast agents can be delivered easily into both phagocytic and nonphagocytic immune cells. Internalization of multifunctional PFD/[InGaP/ZnS QDs] nanoemulsions into immunotherapeutic cells permits the labeled cells to be imaged by both magnetic resonance and fluorescence imaging with little effect on cell viability and function. The results of our study highlight the potential of PFD/[InGaP/ZnS QDs] nanoemulsion as a bimodal imaging nanoprobe for molecular imaging in immune cell-based cancer therapies. | - |
dc.publisher | Elsevier | - |
dc.title | Perfluorodecalin/[InGaP/ZnS quantum dots] nanoemulsions as 19F-MR/optical imaging nanoprobes for the labeling of phagocytic and nonphagocytic immune cells | - |
dc.title.alternative | Perfluorodecalin/[InGaP/ZnS quantum dots] nanoemulsions as 19F-MR/optical imaging nanoprobes for the labeling of phagocytic and nonphagocytic immune cells | - |
dc.type | Article | - |
dc.citation.title | Biomaterials | - |
dc.citation.number | 18 | - |
dc.citation.endPage | 4971 | - |
dc.citation.startPage | 4964 | - |
dc.citation.volume | 31 | - |
dc.contributor.affiliatedAuthor | Yong Taik Lim | - |
dc.contributor.affiliatedAuthor | Bong Hyun Chung | - |
dc.contributor.alternativeName | 임용택 | - |
dc.contributor.alternativeName | 조미영 | - |
dc.contributor.alternativeName | 강지현 | - |
dc.contributor.alternativeName | 노영욱 | - |
dc.contributor.alternativeName | 조지현 | - |
dc.contributor.alternativeName | 홍관수 | - |
dc.contributor.alternativeName | 정진웅 | - |
dc.contributor.alternativeName | 정봉현 | - |
dc.identifier.bibliographicCitation | Biomaterials, vol. 31, no. 18, pp. 4964-4971 | - |
dc.identifier.doi | 10.1016/j.biomaterials.2010.02.065 | - |
dc.subject.keyword | Cell imaging | - |
dc.subject.keyword | Immune cell | - |
dc.subject.keyword | Intracellular delivery | - |
dc.subject.keyword | Nanoparticle | - |
dc.subject.keyword | Perfluorocarbon | - |
dc.subject.keyword | Quantum dots | - |
dc.subject.local | Cell imaging | - |
dc.subject.local | cell imaging | - |
dc.subject.local | Immune Cells | - |
dc.subject.local | immune cell | - |
dc.subject.local | immune cells | - |
dc.subject.local | Immune cells | - |
dc.subject.local | Immune cell | - |
dc.subject.local | Intracellular delivery | - |
dc.subject.local | intracellular delivery | - |
dc.subject.local | Nanoparticles | - |
dc.subject.local | Nanoparticle | - |
dc.subject.local | nanoparticle | - |
dc.subject.local | Perfluorocarbon | - |
dc.subject.local | quantum dots | - |
dc.subject.local | Quantum dot | - |
dc.subject.local | Quantum dots | - |
dc.subject.local | quantum dot | - |
dc.description.journalClass | Y | - |
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