Alkamides from Piper longum and Piper nigrum as inhibitors of IL-6 action = 필발 및 호초로부터 분리된 알카마이드화합물의 IL-6 저해활성
Cited 10 time in 
Metadata Downloads
Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Seung Woong Lee | - |
| dc.contributor.author | Kim myo seon | - |
| dc.contributor.author | Park Mi-hye | - |
| dc.contributor.author | Su-Jin Park | - |
| dc.contributor.author | Woo Song Lee | - |
| dc.contributor.author | Jong Sun Chang | - |
| dc.contributor.author | Mun Chual Rho | - |
| dc.date.accessioned | 2017-04-19T09:18:41Z | - |
| dc.date.available | 2017-04-19T09:18:41Z | - |
| dc.date.issued | 2010 | - |
| dc.identifier.issn | 0253-2964 | - |
| dc.identifier.uri | 10.5012/bkcs.2010.31.04.921 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/9540 | - |
| dc.description.abstract | Blocking of IL-6 has been postulated to be an effective therapy in the pathogenesis of several inflammatory diseases. The current study was performed to examine the potential effects of alkamides isolated from P. longum and P. nigrum on IL-6 induced Stat3 activation and identify the structure-activity relationship of these alkamides in human hepatoma cells. Among 10 alkamides isolated from P. longum and P. nigrum, compounds 6, 7 and 9 were identified as strong inhibitors of IL-6 action, which inhibit IL-6 induced Stat3-dependent luciferase activities. These inhibitory activities were positively influenced by the presence of piperidine moiety. | - |
| dc.publisher | Wiley | - |
| dc.title | Alkamides from Piper longum and Piper nigrum as inhibitors of IL-6 action = 필발 및 호초로부터 분리된 알카마이드화합물의 IL-6 저해활성 | - |
| dc.title.alternative | Alkamides from Piper longum and Piper nigrum as inhibitors of IL-6 action | - |
| dc.type | Article | - |
| dc.citation.title | Bulletin of Korean Chemical Society | - |
| dc.citation.number | 4 | - |
| dc.citation.endPage | 924 | - |
| dc.citation.startPage | 921 | - |
| dc.citation.volume | 31 | - |
| dc.contributor.affiliatedAuthor | Seung Woong Lee | - |
| dc.contributor.affiliatedAuthor | Kim myo seon | - |
| dc.contributor.affiliatedAuthor | Park Mi-hye | - |
| dc.contributor.affiliatedAuthor | Su-Jin Park | - |
| dc.contributor.affiliatedAuthor | Woo Song Lee | - |
| dc.contributor.affiliatedAuthor | Jong Sun Chang | - |
| dc.contributor.affiliatedAuthor | Mun Chual Rho | - |
| dc.contributor.alternativeName | 이승웅 | - |
| dc.contributor.alternativeName | 김묘선 | - |
| dc.contributor.alternativeName | 박미혜 | - |
| dc.contributor.alternativeName | 박수진 | - |
| dc.contributor.alternativeName | 이우송 | - |
| dc.contributor.alternativeName | 장종선 | - |
| dc.contributor.alternativeName | 노문철 | - |
| dc.identifier.bibliographicCitation | Bulletin of Korean Chemical Society, vol. 31, no. 4, pp. 921-924 | - |
| dc.identifier.doi | 10.5012/bkcs.2010.31.04.921 | - |
| dc.subject.keyword | Interleukin-6 | - |
| dc.subject.keyword | Piper longum | - |
| dc.subject.keyword | Piper nigrum | - |
| dc.subject.keyword | Stat3 | - |
| dc.subject.local | IL6 | - |
| dc.subject.local | interukin -6 | - |
| dc.subject.local | Interleukin-6 (IL-6) | - |
| dc.subject.local | IL-6 | - |
| dc.subject.local | Il-6 | - |
| dc.subject.local | interleukin-6 | - |
| dc.subject.local | interleukin-6 (IL-6) | - |
| dc.subject.local | Interleukin-6 | - |
| dc.subject.local | Piper longum | - |
| dc.subject.local | Piper longum L. | - |
| dc.subject.local | Piper nigrum | - |
| dc.subject.local | Piper nigum L. | - |
| dc.subject.local | Signal transducer and activator of transcription 3 (STAT3) | - |
| dc.subject.local | Signal transducer and activator of transcription | - |
| dc.subject.local | Signal transducer and activator of transcription 3 (Stat3) | - |
| dc.subject.local | STAT 3 | - |
| dc.subject.local | STAT3 | - |
| dc.subject.local | Signal transducer and activator of transcription 3 | - |
| dc.subject.local | Stat3 | - |
| dc.subject.local | Signal transducer and activator of transcription factor 3 (STAT3) | - |
| dc.description.journalClass | Y | - |
- Appears in Collections:
- Jeonbuk Branch Institute > Functional Biomaterial Research Center > 1. Journal Articles
- Files in This Item:
There are no files associated with this item.
Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.