Effect of dried garlic flesh and dried garlic juice on body fat and lipid metabolism in 9-month-old rats with diet-induced obesity

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Title
Effect of dried garlic flesh and dried garlic juice on body fat and lipid metabolism in 9-month-old rats with diet-induced obesity
Author(s)
Y J Kang; J Kim; D Kim; Hyun Sun Lee; O Kwon; M K Kim
Bibliographic Citation
Food Science and Biotechnology, vol. 19, no. 3, pp. 589-594
Publication Year
2010
Abstract
The aim of this study was to investigate the effects of dried garlic flesh and dried juice of garlic flesh on the body fat and lipid metabolism of 9-month-old rats with diet-induced obesity. For 8 weeks, the rats were fed either a control diet or experimental diets containing 3 or 5%(w/w) of dried, powdered garlic flesh or garlic juice. In our study, body weight gains and calorie efficiency ratios were the lowest in 5% dried garlic flesh treatment. Hepatic diacylglycerol acyltransferase (DGAT) activities were inhibited relatively to the control for the dried garlic flesh treatments. Fecal total lipid excretion, plasma total lipid, and triglyceride concentrations were significantly improved through the 5% dried garlic flesh treatment. In conclusion, garlic consumption reduced the body fat and improved lipid profile in rats. Especially, consumption of dried garlic flesh was turned out to be more effective than the intake of dried garlic juice.
Keyword
obesitygarlicbody fatdiacylglycerol acyltransferase activity
ISSN
1226-7708
Publisher
South Korea
DOI
http://dx.doi.org/10.1007/s10068-010-0083-1
Type
Article
Appears in Collections:
Ochang Branch Institute > Natural Medicine Research Center > 1. Journal Articles
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