DC Field | Value | Language |
---|---|---|
dc.contributor.author | J W Kwak | - |
dc.contributor.author | Y Kim | - |
dc.contributor.author | H Park | - |
dc.contributor.author | J Y Jang | - |
dc.contributor.author | K K Lee | - |
dc.contributor.author | W Yi | - |
dc.contributor.author | J A Kwak | - |
dc.contributor.author | Song Kyu Park | - |
dc.contributor.author | Hwan Mook Kim | - |
dc.contributor.author | Kiho Lee | - |
dc.contributor.author | Jong Soon Kang | - |
dc.contributor.author | S B Han | - |
dc.contributor.author | B Y Hwang | - |
dc.contributor.author | J T Hong | - |
dc.contributor.author | J K Jung | - |
dc.contributor.author | Y Kim | - |
dc.contributor.author | J Cho | - |
dc.contributor.author | H Lee | - |
dc.date.accessioned | 2017-04-19T09:19:09Z | - |
dc.date.available | 2017-04-19T09:19:09Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0960-894X | - |
dc.identifier.uri | 10.1016/j.bmcl.2010.06.004 | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/9639 | - |
dc.description.abstract | Chroman derivatives exhibited potent inhibitory activity of NF-κB. For SAR, the chroman scaffold was modified with an indoline moiety. A series of indoline-2-carboxylic acid N-(substituted)phenylamide derivatives were synthesized to explore their inhibitory activities of NF-κB and they were also evaluated for cytotoxicity against various cancer cell lines. Since intermediates with Boc showed outstanding results, various substituents in place of the Boc group were introduced additionally and these compounds were also evaluated for SAR. | - |
dc.publisher | Elsevier | - |
dc.title | Structure-activity relationship of indoline-2-carboxylic acid N-(substituted)phenylamide derivatives | - |
dc.title.alternative | Structure-activity relationship of indoline-2-carboxylic acid N-(substituted)phenylamide derivatives | - |
dc.type | Article | - |
dc.citation.title | Bioorganic & Medicinal Chemistry Letters | - |
dc.citation.number | 15 | - |
dc.citation.endPage | 4623 | - |
dc.citation.startPage | 4620 | - |
dc.citation.volume | 20 | - |
dc.contributor.affiliatedAuthor | Song Kyu Park | - |
dc.contributor.affiliatedAuthor | Hwan Mook Kim | - |
dc.contributor.affiliatedAuthor | Kiho Lee | - |
dc.contributor.affiliatedAuthor | Jong Soon Kang | - |
dc.contributor.alternativeName | 곽재환 | - |
dc.contributor.alternativeName | 김요섭 | - |
dc.contributor.alternativeName | 박현정 | - |
dc.contributor.alternativeName | 장재용 | - |
dc.contributor.alternativeName | 이건국 | - |
dc.contributor.alternativeName | 이원희 | - |
dc.contributor.alternativeName | 곽정아 | - |
dc.contributor.alternativeName | 박성규 | - |
dc.contributor.alternativeName | 김환묵 | - |
dc.contributor.alternativeName | 이기호 | - |
dc.contributor.alternativeName | 강종순 | - |
dc.contributor.alternativeName | 한상배 | - |
dc.contributor.alternativeName | 황방연 | - |
dc.contributor.alternativeName | 홍진태 | - |
dc.contributor.alternativeName | 정재경 | - |
dc.contributor.alternativeName | 김영수 | - |
dc.contributor.alternativeName | 조정숙 | - |
dc.contributor.alternativeName | 이희순 | - |
dc.identifier.bibliographicCitation | Bioorganic & Medicinal Chemistry Letters, vol. 20, no. 15, pp. 4620-4623 | - |
dc.identifier.doi | 10.1016/j.bmcl.2010.06.004 | - |
dc.subject.keyword | Cytotoxic activity | - |
dc.subject.keyword | Indoline-2-carboxamide | - |
dc.subject.keyword | NF-κB inhibitors | - |
dc.subject.local | cytotoxic activities | - |
dc.subject.local | cytotoxic activity | - |
dc.subject.local | Cytotoxic activity | - |
dc.subject.local | Indoline-2-carboxamide | - |
dc.subject.local | NF-κB inhibitors | - |
dc.description.journalClass | Y | - |
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