Synthesis of fully-substituted alkenylimidazoles from N-(cyanoalkyl)amides via the In-mediated allylation of nitrile and dehydrative cyclization cascade
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Title
Synthesis of fully-substituted alkenylimidazoles from N-(cyanoalkyl)amides via the In-mediated allylation of nitrile and dehydrative cyclization cascade
Author(s)
Y M Kim; Sangku Lee; S H Kim; K H Kim; J N Kim
Bibliographic Citation
Tetrahedron Letters, vol. 51, no. 45, pp. 5922-5926
Publication Year
2010
Abstract
The reaction of allylindium reagents and N-(cyanoalkyl)amides afforded fully-substituted 4-alkenylimidazoles in moderate yields via the In-mediated Barbier-type allylation of nitrile and the following dehydrative cyclization cascade.