Design, synthesis, and anticancer activities of novel perfluoroalkyltriazole-appended 2'-deoxyuridines
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- Title
- Design, synthesis, and anticancer activities of novel perfluoroalkyltriazole-appended 2'-deoxyuridines
- Author(s)
- S M Park; H Yang; Song Kyu Park; Hwan Mook Kim; B H Kim
- Bibliographic Citation
- Bioorganic & Medicinal Chemistry Letters, vol. 20, no. 19, pp. 5831-5834
- Publication Year
- 2010
- Abstract
- We have focused on the C5-modification of 2′-deoxyuridine with substituted heterocycles for bioactivity, such as antiviral or anticancer activity. Herein, we report a novel class of nucleoside analogues with perfluoroalkyltriazole moiety as an anticancer drug candidate.
- Keyword
- 1,3-Dipolar cycloaddition reaction2′-DeoxyuridineAnticancer activityPerfluoroalkyltriazole
- ISSN
- 0960-894X
- Publisher
- Elsevier
- Full Text Link
- http://dx.doi.org/10.1016/j.bmcl.2010.07.126
- Type
- Article
- Appears in Collections:
- 1. Journal Articles > Journal Articles
- Files in This Item:
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