Current status on plant molecular farming via chloroplast transformation = 엽록체 형질전환 유래 분자 농업의 연구 동향

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Current status on plant molecular farming via chloroplast transformation = 엽록체 형질전환 유래 분자 농업의 연구 동향
Sung Ran MinWon Joong JeongSuk Weon Kim; Jung Hee Lee; H J Chung; Jang Ryol Liu
Bibliographic Citation
Journal of Plant Biotechnology, vol. 37, no. 3, pp. 275-282
Publication Year
Chloroplast transformation in higher plants offers many attractive advantages over nuclear transformation, including a high-level accumulation of foreign proteins, multi-gene expression in single transformation event via transgene stacking in operons and no position effect due to site-specific integration of transgenes by homologous recombination. Most importantly, chloroplast transgenic plants are eco-friendly because their transgenes are maternally inheritance in most crop plants. However, chloroplast transformation system has limited success in crops alike nuclear transformation. In the past two decades, great progress has been made to overcome the limitations of chloroplast transformation, thus expending chloroplast bioreactor to several important crops including soybean, carrot, lettuce, and oilseed. Therefore, it has become possible that chloroplast transformation of crops can be used not only for the improvement of agronomic traits, but also for the production of vaccines and high valuable therapeutic proteins in pharmaceutical industry.
Korea Soc-Assoc-Inst
Appears in Collections:
Division of Research on National Challenges > Plant Systems Engineering Research > 1. Journal Articles
Synthetic Biology and Bioengineering Research Institute > Cell Factory Research Center > 1. Journal Articles
Jeonbuk Branch Institute > Biological Resource Center > 1. Journal Articles
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