DC Field | Value | Language |
---|---|---|
dc.contributor.author | H L Ha | - |
dc.contributor.author | Hye Jun Shin | - |
dc.contributor.author | M A Feitelson | - |
dc.contributor.author | Dae Yeul Yu | - |
dc.date.accessioned | 2017-04-19T09:20:57Z | - |
dc.date.available | 2017-04-19T09:20:57Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1007-9327 | - |
dc.identifier.uri | 10.3748/wjg.v16.i48.6035 | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/9899 | - |
dc.description.abstract | Long term hepatitis B virus (HBV) infection is a major risk factor in pathogenesis of chronic liver diseases, including hepatocellular carcinoma (HCC). The HBV encoded proteins, hepatitis B virus X protein and preS, appear to contribute importantly to the pathogenesis of HCC. Both are associated with oxidative stress, which can damage cellular molecules like lipids, proteins, and DNA during chronic infection. Chronic alcohol use is another important factor that contributes to oxidative stress in the liver. Previous studies reported that treatment with antioxidants, such as curcumin, silymarin, green tea, and vitamins C and E, can protect DNA from damage and regulate liver pathogenesis-related cascades by reducing reactive oxygen species. This review summarizes some of the relationships between oxidative stress and liver pathogenesis, focusing upon HBV and alcohol, and suggests antioxidant therapeutic approaches. ⓒ 2010 Baishideng. | - |
dc.publisher | Baishideng Publishing Group Inc | - |
dc.title | Oxidative stress and antioxidants in hepatic pathogenesis | - |
dc.title.alternative | Oxidative stress and antioxidants in hepatic pathogenesis | - |
dc.type | Article | - |
dc.citation.title | World Journal of Gastroenterology | - |
dc.citation.number | 48 | - |
dc.citation.endPage | 6043 | - |
dc.citation.startPage | 6035 | - |
dc.citation.volume | 16 | - |
dc.contributor.affiliatedAuthor | Hye Jun Shin | - |
dc.contributor.affiliatedAuthor | Dae Yeul Yu | - |
dc.contributor.alternativeName | 하혜린 | - |
dc.contributor.alternativeName | 신혜준 | - |
dc.contributor.alternativeName | Feitelson | - |
dc.contributor.alternativeName | 유대열 | - |
dc.identifier.bibliographicCitation | World Journal of Gastroenterology, vol. 16, no. 48, pp. 6035-6043 | - |
dc.identifier.doi | 10.3748/wjg.v16.i48.6035 | - |
dc.subject.keyword | Alcohol | - |
dc.subject.keyword | Antioxidant | - |
dc.subject.keyword | Chronic liver disease | - |
dc.subject.keyword | Hepatitis B virus | - |
dc.subject.keyword | Hepatitis B virus X protein | - |
dc.subject.keyword | Oxidative stress | - |
dc.subject.local | alcohol | - |
dc.subject.local | Alcohol | - |
dc.subject.local | Alcohols | - |
dc.subject.local | Antioxidants | - |
dc.subject.local | antioxidant | - |
dc.subject.local | Anti-oxidant | - |
dc.subject.local | antioxidants | - |
dc.subject.local | ANTIOXIDANT | - |
dc.subject.local | anti-oxidants | - |
dc.subject.local | Antioxidant | - |
dc.subject.local | chronic liver diseases | - |
dc.subject.local | Chronic liver disease | - |
dc.subject.local | hepatitis B virus (HBV) | - |
dc.subject.local | Hepatitis B Virus | - |
dc.subject.local | Hepatitis B virus (HBV) | - |
dc.subject.local | hepatitis B virus | - |
dc.subject.local | hepatitis B Virus (HBV) | - |
dc.subject.local | Hepatitis B virus | - |
dc.subject.local | hepatitis B virus X protein | - |
dc.subject.local | Hepatitis B virus-X protein | - |
dc.subject.local | Hepatitis B virus X protein | - |
dc.subject.local | hepatitis B virus-X protein | - |
dc.subject.local | Hepatitis B virus X-protein | - |
dc.subject.local | Oxidative stre | - |
dc.subject.local | Oxidative stress | - |
dc.subject.local | OXIDATIVE STRESS | - |
dc.subject.local | Oxidative Stress | - |
dc.subject.local | oxidative stress | - |
dc.description.journalClass | Y | - |
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