Two new lignans from the roots of Pulsatilla koreana

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dc.contributor.authorT D Cuong-
dc.contributor.authorT M Hung-
dc.contributor.authorJ C Kim-
dc.contributor.authorJ I Huh-
dc.contributor.authorS J Kwack-
dc.contributor.authorT S Kang-
dc.contributor.authorJung Hee Kim-
dc.contributor.authorH S Jang-
dc.contributor.authorJ S Choi-
dc.contributor.authorHyeong Kyu Lee-
dc.contributor.authorK Bae-
dc.contributor.authorM S Min-
dc.date.accessioned2017-04-19T09:21:13Z-
dc.date.available2017-04-19T09:21:13Z-
dc.date.issued2011-
dc.identifier.issn0032-0943-
dc.identifier.uri10.1055/s-0030-1250122ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/9938-
dc.description.abstractTwo new lignans, (2R,3R)-2β-(4-hydroxy-3α-methoxybenzyl)-3-(4- hydroxy-3'-methoxybenzyl) -γ- butyrolactone 2-O-(β-D-glucopyranoside) (1) and (1S,2R,3S)-dimethyl-1,2,3,4-tetrahydro-3,6,7-trihydroxy-1-(3,4- dihydroxyphenyl)naphthalene-2,3-dicarboxylate (2) together with nine known compounds (3-11) were isolated from the ethyl acetate fraction of the roots of Pulsatilla koreana. Their chemical structures were established based on physicochemical and spectroscopic data analyses. All isolates were investigated for their inhibition effects against the classical pathway of the complement system. Among them, compound 6 showed significant inhibitory activity with an IC50 value of 75.9 μM, compounds 8 and 9 had moderate effects with IC50 values of 182.2 and 166.5 μM, respectively.-
dc.publisherGeorg Thieme Verlag Kg-
dc.titleTwo new lignans from the roots of Pulsatilla koreana-
dc.title.alternativeTwo new lignans from the roots of Pulsatilla koreana-
dc.typeArticle-
dc.citation.titlePlanta Medica-
dc.citation.number1-
dc.citation.endPage69-
dc.citation.startPage66-
dc.citation.volume77-
dc.contributor.affiliatedAuthorJung Hee Kim-
dc.contributor.affiliatedAuthorHyeong Kyu Lee-
dc.contributor.alternativeNameCuong-
dc.contributor.alternativeNameHung-
dc.contributor.alternativeName김진철-
dc.contributor.alternativeName허정임-
dc.contributor.alternativeName곽승잔-
dc.contributor.alternativeName강태석-
dc.contributor.alternativeName김정희-
dc.contributor.alternativeName장한수-
dc.contributor.alternativeName최재수-
dc.contributor.alternativeName이형규-
dc.contributor.alternativeName배기환-
dc.contributor.alternativeName민병선-
dc.identifier.bibliographicCitationPlanta Medica, vol. 77, no. 1, pp. 66-69-
dc.identifier.doi10.1055/s-0030-1250122-
dc.subject.keywordanticomplement activity-
dc.subject.keywordlignan-
dc.subject.keywordPulsatilla koreana-
dc.subject.keywordRanunculaceae-
dc.subject.localanti-complement activity-
dc.subject.localAnti-complement activity-
dc.subject.localanticomplement activity-
dc.subject.localAnticomplement activity-
dc.subject.locallignan-
dc.subject.localLignans-
dc.subject.localLignan-
dc.subject.locallignans-
dc.subject.localPulsatilla koreana-
dc.subject.localranunculaceae-
dc.subject.localRanunculaceae-
dc.description.journalClassY-
Appears in Collections:
Ochang Branch Institute > Division of National Bio-Infrastructure > Bio-Resource Central Bank > 1. Journal Articles
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