Biological evaluation of KRIBB3 analogs as a microtubule polymerization inhibitor

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dc.contributor.authorSangku Lee-
dc.contributor.authorJ N Kim-
dc.contributor.authorHyeong Kyu Lee-
dc.contributor.authorKab Seog Yoon-
dc.contributor.authorK D Shin-
dc.contributor.authorByoung-Mog Kwon-
dc.contributor.authorDong Cho Han-
dc.date.accessioned2017-04-19T09:21:21Z-
dc.date.available2017-04-19T09:21:21Z-
dc.date.issued2011-
dc.identifier.issn0960-894X-
dc.identifier.uri10.1016/j.bmcl.2010.12.044ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/9960-
dc.description.abstractA series of KRIBB3 analogs were synthesized by modifying substituents at aryl moieties of KRIBB3 for examining structure-activity relationships, and their inhibitory activities on microtubule polymerization were evaluated. The presence of free phenolic hydrogens in aryl moieties of KRIBB3 analogs plays an important role in inhibition of microtubule polymerization.-
dc.publisherElsevier-
dc.titleBiological evaluation of KRIBB3 analogs as a microtubule polymerization inhibitor-
dc.title.alternativeBiological evaluation of KRIBB3 analogs as a microtubule polymerization inhibitor-
dc.typeArticle-
dc.citation.titleBioorganic & Medicinal Chemistry Letters-
dc.citation.number3-
dc.citation.endPage979-
dc.citation.startPage977-
dc.citation.volume21-
dc.contributor.affiliatedAuthorSangku Lee-
dc.contributor.affiliatedAuthorHyeong Kyu Lee-
dc.contributor.affiliatedAuthorKab Seog Yoon-
dc.contributor.affiliatedAuthorByoung-Mog Kwon-
dc.contributor.affiliatedAuthorDong Cho Han-
dc.contributor.alternativeName이상구-
dc.contributor.alternativeName김재녕-
dc.contributor.alternativeName이형규-
dc.contributor.alternativeName윤갑석-
dc.contributor.alternativeName신기덕-
dc.contributor.alternativeName권병목-
dc.contributor.alternativeName한동초-
dc.identifier.bibliographicCitationBioorganic & Medicinal Chemistry Letters, vol. 21, no. 3, pp. 977-979-
dc.identifier.doi10.1016/j.bmcl.2010.12.044-
dc.subject.keywordAnti-mitotic-
dc.subject.keywordCancer-
dc.subject.keywordInhibition-
dc.subject.keywordIsoxazole-
dc.subject.keywordMicrotubule-
dc.subject.localAnti-mitotic-
dc.subject.localAntimitotic-
dc.subject.localCancers-
dc.subject.localcancer-
dc.subject.localCancer-
dc.subject.localinhibition-
dc.subject.localInhibition-
dc.subject.localIsoxazole-
dc.subject.localisoxazole-
dc.subject.localmicrotubule-
dc.subject.localMicrotubule-
dc.description.journalClassY-
Appears in Collections:
Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
Division of Biomedical Research > Personalized Genomic Medicine Research Center > 1. Journal Articles
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