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Results 61-80 of 203 (Search time: 0.005 seconds).

No. Year Title Type
143 2017

2017Article

The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growthCell Death & Disease, vol. 8, no. 6, pp. e2843-e2843Hyun Seung BanBo Kyung Kim; H Lee; H M Kim; D Harmalkar; M Nam; S K Park; K Lee; J T Park; In Hyub Kim, et al.
Article
142 2017

2017Article

Synthesis and biological evaluation of kresoxim-methyl analogues as novel inhibitors of hypoxia-inducible factor (HIF)-1 accumulation in cancer cellsBioorganic & Medicinal Chemistry Letters, vol. 27, no. 13, pp. 3026-3029S Lee; Oh Seok KwonChang-Soo LeeMi Sun WonHyun Seung Ban; C S Ra
Article
141 2017

2017Article

Methyl 3-(3-(4-(2,4,4-trimethylpentan-2-yl)phenoxy)-propanamido)benzoate as a novel and dual malate dehydrogenase (MDH) 1/2 inhibitor targeting cancer metabolismJournal of Medicinal Chemistry, vol. 60, no. 20, pp. 8631-8646R Naik; Hyun Seung Ban; K Jang; I Kim; X Xu; D Harmalkar; S A Shin; M Kim; Bo Kyung Kim; J Park, et al.
Article
140 2017

2017Research Project

RNAi screening에 의한 난치암의 치료 타겟 발굴 및 항암 내성 극복 연구연구책임자 : 원미선 / 사업기간 : 2017.12.01 ~ 2018.11.30
Research Project
139 2017

2017Research Project

유전체 빅데이터 기반 난치성 질환 맞춤치료 원천기술 개발사업 = Genomic big-data driven study of currently untreatable cancers연구책임자 : 박경찬 / 사업기간 : 2017.01.01 ~ 2017.12.31
Research Project
138 2017

2017Research Project

DDIAS가 매개하는 폐암세포의 죽음 조절 네트웍 규명연구책임자 : 원미선 / 사업기간 : 2017.03.01 ~ 2018.02.28
Research Project
137 2017

2017Research Project

다중유전체 분석을 통한 비흡연폐암의 신규치료타겟 발굴 및 기전규명연구책임자 : 박경찬 / 사업기간 : 2017.04.01 ~ 2017.12.31
Research Project
136 2016

2016Patent

H I F-1 α 활성을 저해하는 신규 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 약학조성물JP2014-533208 (2014.03.26) / 6054402 (2016.12.09)김환묵; 원미선; 박성규; 반현승; 김보경정경숙이창우; 이기호
Patent
135 2016

2016Patent

신규한 이치환 아다만틸 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 암 전이 억제용 약학적 조성물US14/724,248 (2015.05.28) / 9,447,063 (2016.09.20)원미선정경숙반현승김보경
Patent
134 2016

2016Patent

H I F-1 α 활성을 저해하는 신규 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 약학조성물CN201280047452.4 (2014.03.27) / ZL201280047452.4 (2016.06.15)김환묵; 원미선; 박성규; 반현승; 김보경정경숙이창우; 이기호
Patent
133 2016

2016Patent

H I F-1 α 활성을 저해하는 신규 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 약학조성물2012316941 (2014.03.18) / 2012316941 (2016.06.09)김환묵; 원미선; 박성규; 반현승; 김보경정경숙이창우; 이기호
Patent
132 2016

2016Patent

H I F-1 α 활성을 저해하는 신규 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 약학조성물US14/347,556 (2014.03.26) / 9,315,507 (2016.04.19)김환묵; 원미선; 박성규; 반현승; 김보경정경숙이창우; 이기호
Patent
131 2016

2016Patent

DDIAS 및 STAT3의 상호작용을 이용한 암 치료제 스크리닝 방법KR10-2014-0105776 (2014.08.14) / 10-1591378 (2016.01.28)원미선김보경정경숙임주영반현승
Patent
130 2016

2016Article

Identification of targets of the HIF-1 inhibitor IDF-11774 using alkyne-conjugated photoaffinity probes = 광친화 화학 프로브를 이용한 IDF-11774의 타겟 확인Bioconjugate Chemistry, vol. 27, no. 8, pp. 1911-1920Hyun Seung Ban; P Naik; H M Kim; Bo Kyung Kim; H Lee; Inhyub Kim; H Ahn; Y Jang; K Jang; Y Eo, et al.
Article
129 2016

2016Article

Shikonin induces apoptosis of lung cancer cells via activation of FOXO3a/EGR1/SIRT1 signaling antagonized by p300 = Foxo3a/Egr1/Sirt1 신호를 통해 암세포사멸을 유도하고 p300에 의해 저해되는 시코닌Biochimica et Biophysica Acta-Molecular Cell Research, vol. 1863, pp. 2584-2593Yun-Ji Jeung; Han-Gyeul Kim; Jiwon Ahn; Ho Joon Lee; Sae Bhom Lee; Mi Sun WonCho Rock JungJoo-Young ImBo Kyung Kim; S K Park, et al.
Article
128 2016

2016Article

A novel malate dehydrogenase 2 inhibitor suppresses hypoxia-inducible factor-1 by regulating mitochondrial respiration = 미토콘드리아 호흡을 저해함으로써 HIF-1을 억제하는 신규 MDH2 저해제PLoS One, vol. 11, no. 9, pp. e0162568-e0162568Hyun Seung Ban; X Xu; K Jang; Inhyub Kim; Bo Kyung Kim; K Lee; Mi Sun Won
Article
127 2016

2016Article

DNA damage induced apoptosis suppressor (DDIAS) is upregulated via ERK5/MEF2B signaling and promotes β-catenin-mediated invasion = ERK5/MEF2B 신호전달을 통한 DDIAS의 발현 증가 및 β-catenin 의 invasion 촉진Biochimica et Biophysica Acta-Gene Regulatory Mechanisms, vol. 1859, pp. 1449-1458Joo-Young Im; Sung Hoon Yoon; Bo Kyung KimHyun Seung Ban; Kyoung-Jae Won; Kyung-Sook Chung; K E Jung; Mi Sun Won
Article
126 2016

2016Article

Data on the transcriptional regulation of DNA damage induced apoptosis suppressor (DDIAS) by ERK5/MEF2B pathway in lung cancer cells = 폐암에서 DDIAS의 ERK5/MEF2B 경로에 의한 DNA 손상의 전사제어Data in Brief, vol. 9, pp. 257-261Joo-Young Im; Sung Hoon Yoon; Bo Kyung KimHyun Seung Ban; Kyung Jae Won; Kyung-Sook Chung; K E Jung; Mi Sun Won
Article
125 2016

2016Article

Properties of a glycogen like polysaccharide produced by a mutant of Escherichia coli lacking glycogen synthase and maltodextrin phosphorylaseCarbohydrate Polymers, vol. 136, pp. 649-655J Y Kwak; M G Kim; Y W Kim; Hyun Seung BanMi Sun Won; J T Park; K H Park
Article
124 2016

2016Article

DNA damage-induced apoptosis suppressor (DDIAS), a novel target of NFATc1, is associated with cisplatin resistance in lung cancerBiochimica et Biophysica Acta-Molecular Cell Research, vol. 1863, no. 1, pp. 40-49Joo-Young Im; K W Lee; Kyoung Jae Won; Bo Kyung KimHyun Seung Ban; Sung Hoon Yoon; Young-Ju Lee; Young Joo Kim; K B Song; Mi Sun Won
Article
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