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Results 1-20 of 39 (Search time: 0.005 seconds).

No. Year Title Type
39 2022

2022Article

Role of the efflux transporters Abcb1 and Abcg2 in the brain distribution of olaparib in miceEuropean Journal of Pharmaceutical Sciences, vol. 173, pp. 106177-106177Yoo-Kyung Song; Min Ju Kim; M S Kim; J H Lee; S J Chung; J S Song; Y J Chae; Kyeong-Ryoon Lee
Article
38 2022

2022Article

In vivo toxicity and pharmacokinetics of polytetrafluoroethylene microplastics in ICR micePolymers, vol. 14, no. 11, pp. 2220-2220S Lee; K K Kang; S E Sung; J H Choi; M Sung; K Y Seong; J Lee; S Kang; S Y Yang; S Lee, et al.
Article
37 2022

2022Article

Highly specific chimeric DNA-RNA-guided genome editing with enhanced CRISPR-Cas12a systemMolecular Therapy-Nucleic Acids, vol. 28, pp. 353-362Hanseop Kim; Wi-Jae Lee; Chan Hyoung Kim; Yeounsun Oh; L W Gwon; H Lee; W Song; J K Hur; Kyung Seob LimKang Jin Jeong, et al.
Article
36 2022

2022Article

Integration of a physiologically based pharmacokinetic and pharmacodynamic model for tegoprazan and its metabolite: application for predicting food effect and intragastric pH alterationsPharmaceutics, vol. 14, no. 6, pp. 1298-1298H C Jeong; M G Kim; Z Wei; Kyeong-Ryoon Lee; J Lee; I S Song; K H Shin
Article
35 2022

2022Article

Model-based prediction of acid suppression and proposal of a new dosing regimen of fexuprazan in humansPharmaceuticals, vol. 15, no. 6, pp. 709-709M S Kim; N Lee; A Lee; Y J Chae; S J Chung; Kyeong-Ryoon Lee
Article
34 2022

2022Article

Regulation of drug transporters by microRNA and implications in disease treatmentJournal of Pharmaceutical Investigation, vol. 52, pp. 23-47Y J Chae; J E Chang; M K Lee; J Lim; K H Shin; Kyeong-Ryoon Lee
Article
33 2022

2022Research Project

천연물 기반 선도물질 선별 및 최적화 기반기술 확립 = Screening of lead molecules from natural porducts and establishment of flatform for optimization technology연구책임자 : 안경섭 / 사업기간 : 2022.01.01 ~ 2022.12.31
Research Project
32 2022

2022Research Project

고효율 3D 다기능 생체조직기반 유효성 및 안전성 스크리닝 서비스연구책임자 : 이경륜 / 사업기간 : 2022.01.01 ~ 2022.12.31
Research Project
31 2021

2021Report

실험동물자원 활용기반 구축 및 지원 사업 = Infra-Building and Services in Biomedical Mouse Resource연구책임자 : 남기환 / 주관부처 : 과학기술정보통신부남기환김형진윤원기원영석; 문옥성; 이기훈서영원; 고영호; 김해림김은경, et al.
Report
30 2021

2021Report

인공지능 등 차세대 기반기술 기반 신약 분야 신규사업 기획연구 = Design New platform for R&D project on Drug Development including AI연구책임자 : 이규선 / 주관부처 : 과학기술정보통신부이규선조성찬김정훈변상원이경륜; 김건호; 송정민김현수
Report
29 2021

2021Article

Development of physiologically based pharmacokinetic model for orally administered fexuprazan in humansPharmaceutics, vol. 13, no. 6, pp. 813-813Y S Jeong; M S Kim; N Lee; A Lee; Y J Chae; S J Chung; Kyeong-Ryoon Lee
Article
28 2021

2021Article

Interplay among conformation, intramolecular hydrogen bonds, and chameleonicity in the membrane permeability and cyclophilin A binding of Mmacrocyclic peptide cyclosporin O derivativesJournal of Medicinal Chemistry, vol. 64, no. 12, pp. 8272-8286D Lee; S Lee; J Choi; Y K Song; Min Ju Kim; D S Shin; M A Bae; Y C Kim; C J Park; Kyeong-Ryoon Lee, et al.
Article
27 2021

2021Article

The development of a functional human small intestinal epithelium model for drug absorptionScience Advances, vol. 7, no. 23, pp. eabh1586-eabh1586Ohman Kwon; Kwang Bo Jung; Kyeong-Ryoon Lee; Ye Seul Son; Hana Lee; Jongjin Kim; Kwangho Kim; Seop Lee; Yoo-Kyung Song; Jaeeun Jung, et al.
Article
26 2021

2021Article

Engineering Yarrowia lipolytica for de novo production of tetraacetyl phytosphingosineJournal of Applied Microbiology, vol. 130, no. 6, pp. 1981-1992Changpyo Han; Min Jeong JangMin Ju Kim; Manho Han; Kyeong-Ryoon Lee; J S Hahn; Jungoh Ahn
Article
25 2021

2021Article

Structure-based modification of pyrazolone derivatives to inhibit mTORC1 by targeting the leucyl-tRNA synthetase-RagD interactionBioorganic Chemistry, vol. 112, pp. 104907-104907J H Kim; K Jung; C Lee; D Song; K Kim; H C Yoo; S J Park; Jong Soon KangKyeong-Ryoon Lee; S Kim, et al.
Article
24 2021

2021Article

Pharmacokinetic estimation models-based approach to predict clinical implications for CYP induction by calcitriol in human cryopreserved hepatocytes and HepaRG cellsPharmaceutics, vol. 13, no. 2, pp. 181-181Y J Chae; M S Kim; S J Chung; M K Lee; Kyeong-Ryoon Lee; H J Maeng
Article
23 2021

2021Article

Bioanalysis of niclosamide in plasma using liquid chromatography-tandem mass and application to pharmacokinetics in rats and dogsJournal of Chromatography B-Analytical Technologies in Biomedical and Life Sciences, vol. 1179, pp. 122862-122862H I Choi; T Kim; S W Lee; J W Kim; Y J Noh; G Y Kim; H J Park; Y J Chae; Kyeong-Ryoon Lee; S J Kim, et al.
Article
22 2021

2021Article

Population pharmacokinetic method to predict within-subject variability using single-period clinical dataPharmaceuticals, vol. 14, no. 2, pp. 114-114W H Kang; J Y Lee; J W Chae; Kyeong-Ryoon Lee; I H Baek; M S Kim; H M Back; S Jung; C Shaffer; R Savic, et al.
Article
21 2021

2021Article

Pharmacokinetic characterization of supinoxin and its physiologically based pharmacokinetic modeling in ratsPharmaceutics, vol. 13, no. 3, pp. 373-373Yoo-Kyung Song; Y H Seol; Min Ju Kim; Jong Woo Jeong; H I Choi; S W Lee; Y J Chae; S Ahn; Y D Gong; Kyeong-Ryoon Lee, et al.
Article
20 2021

2021Research Project

천연물 기반 선도물질 선별 및 최적화 기반기술 확립 = Screening of lead molecules from natural porducts and establishment of flatform for optimization technology연구책임자 : 안경섭 / 사업기간 : 2021.01.01 ~ 2021.12.31
Research Project
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