Disease Target Structure Research Center (질환표적구조연구센터)
Results 21-40 of 91 (Search time: 0.006 seconds).
No. | Year | Title | Type |
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71 | 2020 | 2020Research Project 자궁경부암 유발 HPV 바이러스 단백질-인간 PTP 단백질 복합체에 대한 구조생물학적 연구 = Structural study of the HPV oncoprotein-human PTP protein complex연구책임자 : 구본수 / 사업기간 : 2020.01.01 ~ 2020.12.31 |
Research Project |
70 | 2020 | 2020Research Project 구조기반 단백질 상호작용 조절기술 개발 = Structure-based development of technology for controlling protein-protein interaction연구책임자 : 김승준 / 사업기간 : 2020.01.01 ~ 2020.05.31 |
Research Project |
69 | 2020 | 2020Research Project 인유두종 바이러스 E6, E7 암 유발 단백질 복합체 삼차구조 규명을 통한 발병 기작 이해 = Molecular analysis of the HPV E6, E7 viral oncoprotein complex structure연구책임자 : 구본수 / 사업기간 : 2020.03.01 ~ 2021.02.28 |
Research Project |
68 | 2020 | 2020Research Project 가속기 연구소의 물질조각 탐색 시스템을 활용한 신약후보물질 발굴 = Identification of drug candidates using the fragment screening system of Pohang Accelerator Laboratory연구책임자 : 구본수 / 사업기간 : 2020.03.01 ~ 2020.12.31 |
Research Project |
67 | 2019 | 2019Article Crystal structure of the YAP-binding domain of human TEAD1Bulletin of Korean Chemical Society, vol. 40, no. 1, pp. 74-77Yeajin Mo; Hye Seon Lee; C H Lee; H J Lim; S J Park; Ho-Chul Shin; C H Kim; Seung Jun Kim; Bonsu Ku |
Article |
66 | 2019 | 2019Article Preliminary diffraction analysis of Salmonella Typhi YfdX crystallized in the dimeric state under high pH conditionsBiodesign, vol. 7, no. 3, pp. 57-60Hye Seon Lee; Yeajin Mo; Ho Chul Shin; Seung Jun Kim; Bonsu Ku |
Article |
65 | 2019 | 2019Article Structural and physiological exploration of Salmonella typhi YfdX uncovers its dual function in bacterial antibiotic stress and virulenceFrontiers in Microbiology, vol. 9, pp. 3329-3329Hye Seon Lee; Soohyun Lee; Jun Seob Kim; Hae Ran Lee; Ho Chul Shin; Moo-Seung Lee; K S Jin; C H Kim; Bonsu Ku; Choong-Min Ryu, et al. |
Article |
64 | 2019 | 2019Article Structural basis for recognition of the tumor suppressor protein PTPN14 by the oncoprotein E7 of human papillomavirusPLoS Biology, vol. 17, no. 7, pp. e3000367-e3000367Hye-Yeoung Yoon; Min Wook Kim; Hye Seon Lee; Wantae Kim; Ji Hye Shin; H Kim; Ho Chul Shin; H Park; B H Oh; Won Kon Kim, et al. |
Article |
63 | 2019 | 2019Article Disordered region of cereblon is required for efficient degradation by proteolysis-targeting chimeraScientific Reports, vol. 9, pp. 19654-19654Kidae Kim; D H Lee; Sungryul Park; Seung-Hyun Jo; Bonsu Ku; Sung Goo Park; Byoung Chul Park; Y U Jeon; S Ahn; C H Kang, et al. |
Article |
62 | 2019 | 2019Article Oligomer model of PB1 domain of p62/SQSTM1 based on crystal structure of homo-dimer and calculation of helical characteristicsMolecules and Cells, vol. 42, no. 10, pp. 729-738Dahwan Lim; Hye Seon Lee; Bonsu Ku; Ho Chul Shin; Seung Jun Kim |
Article |
61 | 2019 | 2019Research Project 가속기 연구소의 물질조각 탐색 시스템을 활용한 신약후보물질 발굴 = Identification of drug candidates using the fragment screening system of Pohang Accelerator Laboratory연구책임자 : 구본수 / 사업기간 : 2019.06.01 ~ 2020.02.29 |
Research Project |
60 | 2019 | 2019Research Project 차세대항암제 개발을 위한 타겟 단백질 TEAD4 발현 및 정제연구책임자 : 구본수 / 사업기간 : 2019.11.01 ~ 2020.04.30 |
Research Project |
59 | 2019 | 2019Research Project 자궁경부암 유발 HPV 바이러스 단백질-인간 PTP 단백질 복합체에 대한 구조생물학적 연구 = Structural study of the HPV oncoprotein-human PTP protein complex연구책임자 : 구본수 / 사업기간 : 2019.04.01 ~ 2019.12.31 |
Research Project |
58 | 2019 | 2019Research Project 구조기반 단백질 상호작용 조절기술 개발 = Structure-based development of technology for controlling protein-protein interaction연구책임자 : 김승준 / 사업기간 : 2019.02.01 ~ 2019.12.31 |
Research Project |
57 | 2019 | 2019Research Project 영장류 이용 마약 중독 질환 모델 개발 사업 = Research on drug addiction with non-human primate model연구책임자 : 이상래 / 사업기간 : 2019.08.01 ~ 2019.11.30 |
Research Project |
56 | 2019 | 2019Research Project 난치질환에 대한 구조 기반 고효율 표적제어 기술 개발 = Development of structure-based target-control technology연구책임자 : 박성구 / 사업기간 : 2019.01.01 ~ 2019.12.31 |
Research Project |
55 | 2018 | 2018Report 세포내 자식작용-물질수송 조절단백질 구조 및 기능규명연구 = Structural and functional study on autophagy and versicle trafficking연구책임자 : 구본수 / 주관부처 : 미래창조과학부구본수; 이혜선; 윤혜영; 정다은; 모예진 |
Report |
54 | 2018 | Report | |
53 | 2018 | 2018Article Structural study reveals the temperaturedependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1PLoS One, vol. 13, no. 5, pp. e0197635-e0197635Hye-Yeoung Yun; Jinhyuk Lee; H Kim; Hyojung Ryu; Ho-Chul Shin; B H Oh; Bonsu Ku; Seung Jun Kim |
Article |
52 | 2018 | 2018Article Purification, crystallization, and preliminary X-ray diffraction data analysis for PB1 dimer of P62/SQSTM1Biodesign, vol. 6, no. 4, pp. 100-102Ho Chul Shin; Dahwan Lim; Bonsu Ku; Seung Jun Kim |
Article |