Disease Target Structure Research Center (질환표적구조연구센터)
Results 61-80 of 91 (Search time: 0.005 seconds).
No. | Year | Title | Type |
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31 | 2016 | 2016Article High-resolution crystal structure of the PDZ1 domain of human protein tyrosine phosphatase PTP-BasBiochemical and Biophysical Research Communications, vol. 478, pp. 1205-1210Sang-Ok Lee; Mi-Kyung Lee; Bonsu Ku; Kwang-Hee Bae; Sang Chul Lee; H M Lim; Seung Jun Kim; Seung-Wook Chi |
Article |
30 | 2016 | 2016Article Discovery of novel striatal-enriched protein tyrosine phosphatase inhibitors through structure-based virtual screeningBulletin of Korean Chemical Society, vol. 37, no. 11, pp. 1783-1788Bonsu Ku; Jin A You; Hye Seon Lee; Ho Chul Shin; H Park; Seung Jun Kim |
Article |
29 | 2016 | 2016Article Identification of a highly conserved hypothetical protein TON_0340 as a probable manganese-dependent phosphatasePLoS One, vol. 11, no. 12, pp. e0167549-e0167549Y S Sohn; S G Lee; K H Lee; Bonsu Ku; Ho Chul Shin; S S Cha; Y G Kim; H S Lee; S G Kang; B H Oh |
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28 | 2016 | 2016Article Identification of novel protein tyrosine phosphatase sigma inhibitors promoting neurite extensionBioorganic & Medicinal Chemistry Letters, vol. 26, no. 1, pp. 87-93Hye Seon Lee; Bonsu Ku; T H Park; H Park; J K Choi; Kyu Tae Chang; C H Kim; S E Ryu; Seung Jun Kim |
Article |
27 | 2016 | 2016Article Structural study of the HD-PTP Bro1 domain in a complex with the core region of STAM2, a subunit of ESCRT-0PLoS One, vol. 11, no. 2, pp. e0149113-e0149113Juhyun Lee; Kyoung Jin Oh; Dasom Lee; Bo Yeon Kim; J S Choi; Bonsu Ku; Seung Jun Kim |
Article |
26 | 2016 | 2016Research Project 약물 저항성 바이러스 타겟 신물질의 작용기작에 대한 구조생물학적 분석 = Structural analysis of the functional mechanism of drug-resistant viruses-targeting novel molecules연구책임자 : 구본수 / 사업기간 : 2016.10.01 ~ 2017.04.30 |
Research Project |
25 | 2016 | 2016Research Project 세포내 자식작용-물질수송 조절단백질 구조 및 기능규명연구 = Structural and functional study on autophagy and versicle trafficking연구책임자 : 구본수 / 사업기간 : 2016.01.01 ~ 2016.12.31 |
Research Project |
24 | 2016 | 2016Research Project 구조기반 단백질 상호작용 조절기술 개발 = Structure-based development of technology for controlling protein-protein interaction연구책임자 : 김승준 / 사업기간 : 2016.06.01 ~ 2017.05.31 |
Research Project |
23 | 2016 | 2016Research Project 영장류 이용 마약 중독 질환 모델 개발 사업 = Research on drug addiction with non-human primate model연구책임자 : 이상래 / 사업기간 : 2016.12.01 ~ 2017.11.30 |
Research Project |
22 | 2016 | 2016Research Project 질환표적의 구조 기반 기능제어 기술 개발 = Development of structure-based functional control technology Development of structure-based functional control technology연구책임자 : 지승욱 / 사업기간 : 2016.01.01 ~ 2016.12.31 |
Research Project |
21 | 2015 | 2015Article Structural analysis of the polo-box domain of human Polo-like kinase 2Proteins-Structure Function and Bioinformatics, vol. 83, no. 7, pp. 1201-1208Ju Hee Kim; Bonsu Ku; Kyung S. Lee; Seung Jun Kim |
Article |
20 | 2015 | 2015Article Conversion of cell-survival activity of Akt into apoptotic death of cancer cells by two mutations on the BIM BH3 domainCell Death & Disease, vol. 6, pp. e1804-e1804Jin Sik Kim; Bonsu Ku; T G Woo; A Y Oh; Y S Jung; Y M Soh; J H Yeom; K Lee; B J Park; B H Oh, et al. |
Article |
19 | 2015 | 2015Research Project 영장류 이용 마약 중독 질환 모델 개발 사업 = Research on drug addiction with non-human primate model연구책임자 : 이상래 / 사업기간 : 2015.12.01 ~ 2016.11.30 |
Research Project |
18 | 2015 | 2015Research Project 화합물 WCI-1004의 최적화를 통한 무독성 항암제 개발 = Optimization and low-side effect anticancer drug development of WCI-1004연구책임자 : 김보연 / 사업기간 : 2015.12.26 ~ 2016.12.25 |
Research Project |
17 | 2015 | 2015Research Project 타이로신 특이적 탈인산화효소군의 대용량 구조 규명 연구 = High-throughput structure determination of protein tyrosine phophatases연구책임자 : 김승준 / 사업기간 : 2015.09.01 ~ 2016.08.31 |
Research Project |
16 | 2015 | 2015Research Project 세포내 자식작용-물질수송 조절단백질 구조 및 기능규명연구 = Structural and functional study on autophagy and versicle trafficking연구책임자 : 구본수 / 사업기간 : 2015.05.01 ~ 2015.12.31 |
Research Project |
15 | 2015 | 2015Research Project 구조기반 단백질 상호작용 조절기술 개발 = Structure-based development of technology for controlling protein-protein interaction연구책임자 : 김승준 / 사업기간 : 2015.06.01 ~ 2016.05.31 |
Research Project |
14 | 2014 | Report | |
13 | 2014 | 2014Article The family-wide structure and function of human dual-specificity protein phosphatases = 인간 이중특이성 탈인산화효소들의 구조와 기능Acta Crystallographica Section D-Biological Crystallography, vol. 70, no. 2, pp. 421-435Dae Gwin Jeong; C H Wei; Bonsu Ku; T J Jeon; P N Chien; J K Kim; S Y Park; H S Hwang; S Y Ryu; H Park, et al. |
Article |
12 | 2014 | 2014Article Discovery of novel protein tyrosine phosphatase sigma inhibitors through the virtual screening with modified scoring functionMedicinal Chemistry Research, vol. 23, no. 2, pp. 1016-1022H Park; Hye Seon Lee; Bonsu Ku; Seung Jun Kim |
Article |