Disease Target Structure Research Center (질환표적구조연구센터)
Results 61-80 of 172 (Search time: 0.006 seconds).
No. | Year | Title | Type |
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112 | 2019 | 2019Article Differential effects, on oncogenic pathway signalling, by derivatives of the HNF4 α inhibitor BI6015British Journal of Cancer, vol. 120, no. 5, pp. 488-498J H Kim; H J Eom; GyuTae Lim; S Park; Jinhyuk Lee; S Nam; Y H Kim; J H Jeong |
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111 | 2019 | 2019Article Isolation and characterization of the stress-tolerant Candida tropicalis YHJ1 and evaluation of its xylose reductase for xylitol production from acid pretreatment wastewaterFrontiers in Bioengineering and Biotechnology, vol. 7, pp. 138-138Seonghun Kim; Jinhyuk Lee; Bong Hyun Sung |
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110 | 2019 | 2019Article Tannic acid, a novel histone acetyltransferase inhibitor, prevents non-alcoholic fatty liver disease both in vivo and in vitro modelMolecular Metabolism, vol. 19, pp. 34-48M Y Chung; J H Song; Jinhyuk Lee; E J Shin; J H Park; S H Lee; J T Hwang; H K Choi |
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109 | 2019 | 2019Article Baicalein as a potential inhibitor against BACE1 and AChE: mechanistic comprehension through in vitro and computational approachesNutrients, vol. 11, no. 11, pp. 2694-2694J Han; Y Ji; K Youn; Gyu Tae Lim; Jinhyuk Lee; D H Kim; M Jun |
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108 | 2019 | 2019Research Project 당질 유전자 교정 기술을 이용한 인간모사 마우스모델 개발 사업 = Generation of glycan-humanized model mouse for non-clinical study연구책임자 : 고정헌 / 사업기간 : 2019.01.01 ~ 2019.12.31 |
Research Project |
107 | 2018 | 2018Article Identification of a rare homozygous c.790C>T variation in the TFB2M gene in Korean patients with autism spectrum disorderBiochemical and Biophysical Research Communications, vol. 507, no. 1, pp. 148-154C B Park; V N Choi; J B Jun; J H Kim; Y Lee; Jinhyuk Lee; GyuTae Lim; J Kim; S Y Jeong; S Y Yim |
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106 | 2018 | 2018Research Project 대사플럭스 제어 및 효소활성 최적화 기술 개발연구책임자 : 성봉현 / 사업기간 : 2018.03.01 ~ 2019.02.28 |
Research Project |
105 | 2018 | 2018Research Project 미래형 유전자편집 항암면역세포치료제 개발연구책임자 : 김태돈 / 사업기간 : 2018.09.17 ~ 2019.09.16 |
Research Project |
104 | 2018 | 2018Research Project 연구 빅데이터 기반 바이오 마커 발굴 및 유효물질 도출 기술 개발연구책임자 : 이진혁 / 사업기간 : 2018.05.01 ~ 2018.10.31 |
Research Project |
103 | 2018 | 2018Article BACE1 inhibition by genistein: biological evaluation, kinetic analysis, and molecular docking simulationJournal of Medicinal Food, vol. 21, no. 4, pp. 416-420K Youn; J H Park; S Lee; S Lee; Jinhyuk Lee; E Y Yun; W S Jeong; M Jun |
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102 | 2018 | 2018Article Effects of osmolytes on the refolding of recombinant Pelodiscus sinensis brain-type creatine kinaseProcess Biochemistry, vol. 68, pp. 83-92X B Sun; Gyu Tae Lim; Jinhyuk Lee; J X Wan; H Z Lin; J B Yang; Q Wang; Y D Park |
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101 | 2018 | 2018Article Structural study reveals the temperaturedependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1PLoS One, vol. 13, no. 5, pp. e0197635-e0197635Hye-Yeoung Yun; Jinhyuk Lee; H Kim; Hyojung Ryu; Ho-Chul Shin; B H Oh; Bonsu Ku; Seung Jun Kim |
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100 | 2018 | 2018Article In silico docking and in vitro approaches towards BACE1 and cholinesterases inhibitory effect of citrus flavanonesMolecules, vol. 23, no. 7, pp. 1509-1509S Lee; K Youn; Gyu Tae Lim; Jinhyuk Lee; M Jun |
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99 | 2018 | 2018Article Fisetin inhibits TNF-α/NF-κB-induced IL-8 expression by targeting PKCδ in human airway epithelial cellsCytokine, vol. 108, pp. 247-254Seoghyun Lee; H Ro; H J In; Ji Hee Choi; Mun-Ock Kim; Jinhyuk Lee; S T Hong; Su Ui Lee |
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98 | 2018 | 2018Article Evolution of enzymes with new specificity by high-throughput screening using DmpR-based genetic circuits and multiple flow cytometry roundsScientific Reports, vol. 8, pp. 2659-2659Kil Koang Kwon; Dae-Hee Lee; Su Jin Kim; Su-Lim Choi; Eugene Rha; Soo Jin Yeom; B Subhadra; Jinhyuk Lee; K J Jeong; Seung Goo Lee |
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97 | 2018 | 2018Article Inhibition of α-glucosidase by 2-thiobarbituric acid: molecular dynamics simulation integrating parabolic noncompetitive inhibition kineticsProcess Biochemistry, vol. 65, pp. 62-70X Y Qin; Jinhyuk Lee; L Zheng; J M Yang; Y Gong; Y D Park |
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96 | 2018 | 2018Article Piscroside C inhibits TNF-α/NF-κB pathway by the suppression of PKCδ activity for TNF-RSC formation in human airway epithelial cellsPhytomedicine, vol. 40, pp. 148-157Su Ui Lee; Seoghyun Lee; H Ro; Ji Hee Choi; Hyung Won Ryu; Mun-Ock Kim; Heung Joo Yuk; Jinhyuk Lee; S T Hong; Sei-Ryang Oh |
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95 | 2018 | 2018Article Inhibitory effect of raspberry ketone on α-glucosidase : docking simulation integrating inhibition kineticsInternational Journal of Biological Macromolecules, vol. 113, pp. 212-218X L Xiong; L M Yue; Gyu Tae Lim; J M Yang; Jinhyuk Lee; Y D Park |
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94 | 2018 | 2018Article Inhibitory effect of pyrogallol on α-glucosidase : integrating docking simulations with inhibition kineticsInternational Journal of Biological Macromolecules, vol. 112, pp. 686-693L Zheng; Jinhyuk Lee; L M Yue; Gyu Tae Lim; J M Yang; Z M Ye; Y D Park |
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93 | 2018 | 2018Article Molecular dynamics simulation integrating the inhibition kinetics of hydroxysafflor yellow A on α-glucosidaseJournal of Biomolecular Structure & Dynamics, vol. 36, no. 4, pp. 830-840Y Xu; Jinhyuk Lee; Y D Park; J M Yang; J Zheng; Q Zhang |
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