Natural Medicine Research Center (천연물연구센터)
Results 61-80 of 88 (Search time: 0.008 seconds).
No. | Year | Title | Type |
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28 | 2014 | 2014Report 혁신 신약 타깃 검증 연구 플랫폼 = Integrative discovery research platform for innovative medicine연구책임자 : 이상구 / 주관부처 : 미래창조과학부이상구; 이현선; 조성찬; 김선홍; 김문옥 |
Report |
27 | 2014 | 2014Article Discovery of a novel class of diacylglycerol acyltransferase 2 inhibitors with a 1H-Pyrrolo[2,3-b]pyridine core = DGAT2의 신규 억제물질 발굴Biological & Pharmaceutical Bulletin, vol. 37, no. 10, pp. 1655-1660Mun-Ock Kim; Su Ui Lee; Kwang Man Choi; Sangku Lee; Hyeong Ki Kim; Hyun Ju Kang; Miri Choi; Eun Bin Kwon; Myung Ji Kang; Sun Hong Kim, et al. |
Article |
26 | 2014 | 2014Research Project 해외식물 소재로부터 대사질환용 전임상 후보소재 발굴 = Discovery of preclinical candidates for the prevention and treatment of metabolic disease from foreign plants연구책임자 : 이현선 / 사업기간 : 2014.10.01 ~ 2015.09.30 |
Research Project |
25 | 2014 | 2014Research Project 난치질환 치료제 후보물질 발굴을 위한 유효물질 탐색 = Drug screening for the discovery of incurable diseases therapeutic candidates연구책임자 : 김보연 / 사업기간 : 2014.09.10 ~ 2014.12.31 |
Research Project |
24 | 2014 | 2014Research Project GPAT1 억제제 탐색과 지방간 및 인슐린저항성 개선 효과 검증연구책임자 : 김문옥 / 사업기간 : 2014.06.01 ~ 2015.05.31 |
Research Project |
23 | 2014 | 2014Research Project 혁신 신약 타깃 검증 연구 플랫폼 = Integrative discovery research platform for innovative medicine연구책임자 : 이상구 / 사업기간 : 2014.01.01 ~ 2014.12.31 |
Research Project |
22 | 2013 | 2013Article Discovery of indolyl acrylamide derivatives as human diacylglycerol acyltransferase-2 selective inhibitorsOrganic & Biomolecular Chemistry, vol. 11, no. 5, pp. 849-858K Lee; M Kim; B Lee; J Goo; J Kim; R Naik; Jee Hee Seo; Mun-Ock Kim; Y Byun; G Y Song, et al. |
Article |
21 | 2013 | 2013Article Verrucarin A enhances TRAIL-induced apoptosis via NF-κB-mediated Fas overexpressionFood and Chemical Toxicology, vol. 55, no. 1, pp. 1-7R G P T Jayasooriya; D O Moon; S G Yun; Y H Choi; Y Asami; Mun-Ock Kim; Jae-Hyuk Jang; Bo Yeon Kim; Jong Seog Ahn; G Y Kim |
Article |
20 | 2013 | 2013Article Xestospongin C induces monocytic differentiation of HL60 cells through activation of the ERK pathwayFood and Chemical Toxicology, vol. 55, pp. 505-512D O Moon; Y Asami; Mun-Ock Kim; Jae-Hyuk Jang; Bo Yeon Kim; Jong Seog Ahn; G Y Kim; S G Yun |
Article |
19 | 2013 | 2013Article β-Arrestin 2 mediates G protein-coupled receptor 43 signals to Nuclear Factor-kappaB = 베타어레스틴 2에 의한 GPR43-NFkB 신호전달계의 조절Biological & Pharmaceutical Bulletin, vol. 36, no. 11, pp. 1754-1759Su Ui Lee; H J In; M S Kwon; Bi-oh Park; M Jo; Mun-Ock Kim; Sungchan Cho; Sangku Lee; Hyun Jun Lee; Y S Kwak, et al. |
Article |
18 | 2013 | 2013Article Water-soluble chitosan sensitizes apoptosis in human leukemia cells via the downregulation of Bcl-2 and dephosphorylation of AktJournal of Food Biochemistry, vol. 37, no. 3, pp. 270-277Mun-Ock Kim; D O Moon; C H Kang; Y H Choi; J D Lee; G Y Kim |
Article |
17 | 2013 | 2013Article Aralia cordata inhibits triacylglycerol biosynthesis in HepG2 cellsJournal of Medicinal Food, vol. 16, no. 12, pp. 1108-1114Mun-Ock Kim; S H Lee; J H Seo; I S Kim; Ah Reum Han; D O Moon; Sungchan Cho; L Cui; J Kim; Hyun Sun Lee |
Article |
16 | 2013 | 2013Article Combined treatment with verrucarin A and tumor necrosis factor-α sensitizes apoptosis by overexpression of nuclear factor-kappaB-mediated FasEnvironmental Toxicology and Pharmacology, vol. 36, no. 2, pp. 303-310R G P T Jayasooriya; D O Moon; S R Park; Y H Choi; Y Asami; Mun-Ock Kim; Jae-Hyuk Jang; Bo Yeon Kim; Jong Seog Ahn; G Y Kim |
Article |
15 | 2013 | 2013Article Identification and validation of a selective small molecule inhibitor targeting the diacylglycerol acyltransferase 2 activity = 디아실글리세롤 아실트랜스퍼라제 선택적 억제물질 발굴 및 검증Biological & Pharmaceutical Bulletin, vol. 36, no. 7, pp. 1167-1173Mun-Ock Kim; Su Ui Lee; Hyun Jun Lee; Kwangman Choi; Hyeongki Kim; Sangku Lee; Soo Jin Oh; Sunhong Kim; Jong Soon Kang; Hyun Sun Lee, et al. |
Article |
14 | 2013 | 2013Research Project 혁신 신약 타깃 검증 연구 플랫폼 = Integrative discovery research platform for innovative medicine연구책임자 : 이상구 / 사업기간 : 2013.01.01 ~ 2013.12.31 |
Research Project |
13 | 2013 | 2013Research Project 해외식물 소재로부터 대사질환용 전임상 후보소재 발굴 = Discovery of preclinical candidates for the prevention and treatment of metabolic disease from foreign plants연구책임자 : 이현선 / 사업기간 : 2013.10.01 ~ 2014.09.30 |
Research Project |
12 | 2013 | 2013Research Project 생명(연)-RIKEN 화학생물 공동연구센터 = KRIBB-RIKEN Collaboration Research Center for Chemical Biology연구책임자 : 안종석 / 사업기간 : 2013.09.01 ~ 2014.08.31 |
Research Project |
11 | 2013 | 2013Research Project GPAT1 억제제 탐색과 지방간 및 인슐린저항성 개선 효과 검증연구책임자 : 김문옥 / 사업기간 : 2013.06.01 ~ 2014.05.31 |
Research Project |
10 | 2013 | 2013Research Project 혁신 의약 타깃 기반 대사성 및 염증성 질환 선도물질 창출 = Discovery Research Aimed at In Vivo Proof-of-Concept of Novel Therapeutic Targets for Metabolic or Inflammatory Diseases연구책임자 : 조성찬 / 사업기간 : 2013.11.01 ~ 2014.10.31 |
Research Project |
9 | 2012 | 2012Article Discovery of a novel series of benzimidazole derivatives as diacylglycerol acyltransferase inhibitorsBioorganic & Medicinal Chemistry Letters, vol. 22, no. 24, pp. 7456-7460K Lee; J I Goo; H Y Jung; M Kim; S K Boovanahalli; H R Park; Mun-Ock Kim; D H Kim; Hyun Sun Lee; Y Choi |
Article |