Gene silencing by siRNA microhydrogels via polymeric nanoscale condensation
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | C A Hong | - |
| dc.contributor.author | S H Lee | - |
| dc.contributor.author | J S Kim | - |
| dc.contributor.author | J W Park | - |
| dc.contributor.author | K H Bae | - |
| dc.contributor.author | Hye Jung Mok | - |
| dc.contributor.author | T G Park | - |
| dc.contributor.author | H Lee | - |
| dc.date.accessioned | 2017-04-19T09:25:21Z | - |
| dc.date.available | 2017-04-19T09:25:21Z | - |
| dc.date.issued | 2011 | - |
| dc.identifier.issn | 0002-7863 | - |
| dc.identifier.uri | 10.1021/ja2056984 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/10317 | - |
| dc.description.abstract | The first attempt to prepare biologically active siRNA-based microhydrogels is reported. The self-assembled microhydrogels were fabricated using sense/antisense complementary hybridization between single-stranded linear and Y-shaped trimeric siRNAs. The siRNA microhydrogels were condensed using a popular cationic polymer such as LPEI to form compact, stable siRNA/polymeric nanoparticles that exhibited superb cellular uptake efficiency and gene silencing activity. | - |
| dc.publisher | Amer Chem Soc | - |
| dc.title | Gene silencing by siRNA microhydrogels via polymeric nanoscale condensation | - |
| dc.title.alternative | Gene silencing by siRNA microhydrogels via polymeric nanoscale condensation | - |
| dc.type | Article | - |
| dc.citation.title | Journal of American Chemical Society | - |
| dc.citation.number | 35 | - |
| dc.citation.endPage | 13917 | - |
| dc.citation.startPage | 13914 | - |
| dc.citation.volume | 133 | - |
| dc.contributor.affiliatedAuthor | Hye Jung Mok | - |
| dc.contributor.alternativeName | 홍철암 | - |
| dc.contributor.alternativeName | 이수현 | - |
| dc.contributor.alternativeName | 김지선 | - |
| dc.contributor.alternativeName | 박지원 | - |
| dc.contributor.alternativeName | 배기현 | - |
| dc.contributor.alternativeName | 목혜정 | - |
| dc.contributor.alternativeName | 박태관 | - |
| dc.contributor.alternativeName | 이해신 | - |
| dc.identifier.bibliographicCitation | Journal of American Chemical Society, vol. 133, no. 35, pp. 13914-13917 | - |
| dc.identifier.doi | 10.1021/ja2056984 | - |
| dc.description.journalClass | Y | - |
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