A novel small molecule facilitates the reprogramming of human somatic cells into a pluripotent state and supports the maintenance of an undifferentiated state of human pluripotent stem cells

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dc.contributor.authorJung Woon Lee-
dc.contributor.authorY Xia-
dc.contributor.authorMi Young Son-
dc.contributor.authorG Jin-
dc.contributor.authorBinna Seol-
dc.contributor.authorMin-Jeong Kim-
dc.contributor.authorMyung Jin Son-
dc.contributor.authorM Do-
dc.contributor.authorM Lee-
dc.contributor.authorD Kim-
dc.contributor.authorK Lee-
dc.contributor.authorYee Sook Cho-
dc.date.accessioned2017-04-19T09:35:56Z-
dc.date.available2017-04-19T09:35:56Z-
dc.date.issued2012-
dc.identifier.issn1433-7851-
dc.identifier.uri10.1002/anie.201206691ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/11100-
dc.description.abstractBooster of pluripotency: RSC133, a new synthetic derivative of indoleacrylic acid/indolepropionic acid, exhibits dual activity by inhibiting histone deacetylase and DNA methyltransferase. Furthermore it potently improves the reprogramming of human somatic cells into a pluripotent state and aids the growth and maintenance of human pluripotent stem cells (hPSCs).-
dc.publisherWiley-
dc.titleA novel small molecule facilitates the reprogramming of human somatic cells into a pluripotent state and supports the maintenance of an undifferentiated state of human pluripotent stem cells-
dc.title.alternativeA novel small molecule facilitates the reprogramming of human somatic cells into a pluripotent state and supports the maintenance of an undifferentiated state of human pluripotent stem cells-
dc.typeArticle-
dc.citation.titleAngewandte Chemie-International Edition-
dc.citation.number50-
dc.citation.endPage12513-
dc.citation.startPage12509-
dc.citation.volume51-
dc.contributor.affiliatedAuthorJung Woon Lee-
dc.contributor.affiliatedAuthorMi Young Son-
dc.contributor.affiliatedAuthorBinna Seol-
dc.contributor.affiliatedAuthorMin-Jeong Kim-
dc.contributor.affiliatedAuthorMyung Jin Son-
dc.contributor.affiliatedAuthorYee Sook Cho-
dc.contributor.alternativeName이정운-
dc.contributor.alternativeNameXia-
dc.contributor.alternativeName손미영-
dc.contributor.alternativeNameJin-
dc.contributor.alternativeName설빛나-
dc.contributor.alternativeName김민정-
dc.contributor.alternativeName손명진-
dc.contributor.alternativeName도미솔-
dc.contributor.alternativeName이민호-
dc.contributor.alternativeName김동섭-
dc.contributor.alternativeName이경-
dc.contributor.alternativeName조이숙-
dc.identifier.bibliographicCitationAngewandte Chemie-International Edition, vol. 51, no. 50, pp. 12509-12513-
dc.identifier.doi10.1002/anie.201206691-
dc.subject.keywordgene expression-
dc.subject.keywordpluripotency-
dc.subject.keywordreprogramming-
dc.subject.keywordsmall molecules-
dc.subject.keywordstem cells-
dc.subject.localGene Expression-
dc.subject.localGene expression-
dc.subject.localgene expression-
dc.subject.localpluripotency-
dc.subject.localPluripotency-
dc.subject.localreprogramming-
dc.subject.localReprogramming-
dc.subject.localsmall molecules-
dc.subject.localstem cells-
dc.subject.localstem cell-
dc.subject.localStem cell-
dc.subject.localStem cells-
dc.subject.localStem Cell-
dc.description.journalClassY-
Appears in Collections:
Division of Research on National Challenges > Environmental diseases research center > 1. Journal Articles
Division of Research on National Challenges > Stem Cell Convergenece Research Center > 1. Journal Articles
Division of A.I. & Biomedical Research > Immunotherapy Research Center > 1. Journal Articles
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