DC Field | Value | Language |
---|---|---|
dc.contributor.author | J S Ryu | - |
dc.contributor.author | Kyu Tae Chang | - |
dc.contributor.author | J T Lee | - |
dc.contributor.author | M U Lim | - |
dc.contributor.author | H K Min | - |
dc.contributor.author | Y J Na | - |
dc.contributor.author | S B Lee | - |
dc.contributor.author | G Moussavou | - |
dc.contributor.author | Sun-Uk Kim | - |
dc.contributor.author | Ji Su Kim | - |
dc.contributor.author | K Ko | - |
dc.contributor.author | K Ko | - |
dc.contributor.author | K A Hwang | - |
dc.contributor.author | E J Jeong | - |
dc.contributor.author | Jeong Woong Lee | - |
dc.contributor.author | Y K Choo | - |
dc.date.accessioned | 2017-04-19T09:36:12Z | - |
dc.date.available | 2017-04-19T09:36:12Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 1225-8687 | - |
dc.identifier.uri | 10.5483/BMBRep.2012.45.12.138 | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/11130 | - |
dc.description.abstract | Gangliosides play important roles in the control of several biological processes, including proliferation and transmembrane signaling. In this study, we demonstrate the effect of ganglioside GM1 on the proliferation of mouse induced pluripotent stem cells (miPSCs). The proliferation rate of miPSCs was lower than in mouse embryonic stem cells (mESCs).Fluorescence activated cell sorting analysis showed that the percentage of cells in the G2/M phase in miPSCs was lower than that in mESCs. GM1 was expressed in mESCs, but not miPSCs. To confirm the role of GM1 in miPSC proliferation, miPSCs were treated with GM1. GM1-treated miPSCs exhibited increased cell proliferation and a larger number of cells in the G2/M phase. Furthermore, phosphorylation of mitogen-activated protein kinases was increased in GM1- treated miPSCs. | - |
dc.publisher | Korea Soc-Assoc-Inst | - |
dc.title | Ganglioside GM1 influences the proliferation rate of mouse induced pluripotent stem cells | - |
dc.title.alternative | Ganglioside GM1 influences the proliferation rate of mouse induced pluripotent stem cells | - |
dc.type | Article | - |
dc.citation.title | BMB Reports | - |
dc.citation.number | 12 | - |
dc.citation.endPage | 718 | - |
dc.citation.startPage | 713 | - |
dc.citation.volume | 45 | - |
dc.contributor.affiliatedAuthor | Kyu Tae Chang | - |
dc.contributor.affiliatedAuthor | Sun-Uk Kim | - |
dc.contributor.affiliatedAuthor | Ji Su Kim | - |
dc.contributor.affiliatedAuthor | Jeong Woong Lee | - |
dc.contributor.alternativeName | 류재성 | - |
dc.contributor.alternativeName | 장규태 | - |
dc.contributor.alternativeName | 이주택 | - |
dc.contributor.alternativeName | 임맑음 | - |
dc.contributor.alternativeName | 민현기 | - |
dc.contributor.alternativeName | 나윤주 | - |
dc.contributor.alternativeName | 이수빈 | - |
dc.contributor.alternativeName | Moussavou | - |
dc.contributor.alternativeName | 김선욱 | - |
dc.contributor.alternativeName | 김지수 | - |
dc.contributor.alternativeName | 고기남 | - |
dc.contributor.alternativeName | 고기성 | - |
dc.contributor.alternativeName | 황경아 | - |
dc.contributor.alternativeName | 정은정 | - |
dc.contributor.alternativeName | 이정웅 | - |
dc.contributor.alternativeName | 추영국 | - |
dc.identifier.bibliographicCitation | BMB Reports, vol. 45, no. 12, pp. 713-718 | - |
dc.identifier.doi | 10.5483/BMBRep.2012.45.12.138 | - |
dc.subject.keyword | Cell cycle | - |
dc.subject.keyword | Ganglioside GM1 | - |
dc.subject.keyword | MAP kinase | - |
dc.subject.keyword | Mouse induced pluripotent stem cells (miPSCs) | - |
dc.subject.keyword | Proliferation | - |
dc.subject.local | cell cycle | - |
dc.subject.local | Cell cycle | - |
dc.subject.local | ganglioside GM1 | - |
dc.subject.local | Ganglioside GM1 | - |
dc.subject.local | MAP kinases | - |
dc.subject.local | map kinase | - |
dc.subject.local | MAP kinase | - |
dc.subject.local | Mouse induced pluripotent stem cells (miPSCs) | - |
dc.subject.local | proliferation | - |
dc.subject.local | Proliferation | - |
dc.description.journalClass | Y | - |
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