Cytotoxic sesterterpenoids isolated from the marine sponge Scalarispongia sp.

Cited 10 time in scopus
Metadata Downloads
Title
Cytotoxic sesterterpenoids isolated from the marine sponge Scalarispongia sp.
Author(s)
Y J Lee; J W Lee; D G Lee; H S Lee; Jong Soon Kang; Ji Eun Yun
Bibliographic Citation
International Journal of Molecular Sciences, vol. 15, no. 11, pp. 20045-20053
Publication Year
2014
Abstract
Eight scalarane sesterterpenoids, including four new compounds, were isolated from the marine sponge Scalarispongia sp. The structures of the new compounds were elucidated by 2D-NMR and HRMS analyses. All of the isolated compounds, with the exception of 16-O-deacetyl-12,16-epi-scalarolbutanolide, showed significant in vitro cytotoxicity (GI50 values down to 5.2 μM) against six human cancer cell lines.
Keyword
CytotoxicityScalaraneScalarispongiaSesterterpenoidSponge
ISSN
1422-0067
Publisher
MDPI
DOI
http://dx.doi.org/10.3390/ijms151120045
Type
Article
Appears in Collections:
Ochang Branch Institute > Division of National Bio-Infrastructure > Laboratory Animal Resource & Research Center > 1. Journal Articles
Files in This Item:

Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.