New neo-lignan from Acanthopanax senticosus with protein tyrosine phosphatase 1B inhibitory activity
Cited 27 time in 
Metadata Downloads
Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | J L Li | - |
| dc.contributor.author | N Li | - |
| dc.contributor.author | S S Xing | - |
| dc.contributor.author | N Zhang | - |
| dc.contributor.author | B B Li | - |
| dc.contributor.author | J G Chen | - |
| dc.contributor.author | Jong Seog Ahn | - |
| dc.contributor.author | L Cui | - |
| dc.date.accessioned | 2018-04-19T05:18:36Z | - |
| dc.date.available | 2018-04-19T05:18:36Z | - |
| dc.date.issued | 2017 | - |
| dc.identifier.issn | 0253-6269 | - |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/17649 | - |
| dc.description.abstract | New neo-lignan, (7S, 8R)-3-hydroxyl-4-methoxyl-balanophonin (1), together with seven known compounds (2？8) were isolated from the EtOAc-soluble extract of Acanthopanax senticosus. The structure of the new neo-lignan was elucidated with spectroscopic and physico-chemical analyses. All the isolates were evaluated for in vitro inhibitory activity against PTP1B, VHR and PP1. Among them, the new compound (1) was found to exhibit selective inhibitory activity on PTP1B with IC 50 value 15.2 ± 1.4 μM. ⓒ 2015, The Pharmaceutical Society of Korea. | - |
| dc.publisher | Pharmaceutical Soc Korea | - |
| dc.title | New neo-lignan from Acanthopanax senticosus with protein tyrosine phosphatase 1B inhibitory activity | - |
| dc.title.alternative | New neo-lignan from Acanthopanax senticosus with protein tyrosine phosphatase 1B inhibitory activity | - |
| dc.type | Article | - |
| dc.citation.title | Archives of Pharmacal Research | - |
| dc.citation.number | 11 | - |
| dc.citation.endPage | 1270 | - |
| dc.citation.startPage | 1265 | - |
| dc.citation.volume | 40 | - |
| dc.contributor.affiliatedAuthor | Jong Seog Ahn | - |
| dc.contributor.alternativeName | Li | - |
| dc.contributor.alternativeName | Li | - |
| dc.contributor.alternativeName | - | |
| dc.contributor.alternativeName | Zhang | - |
| dc.contributor.alternativeName | Li | - |
| dc.contributor.alternativeName | Chen | - |
| dc.contributor.alternativeName | 안종석 | - |
| dc.contributor.alternativeName | Cui | - |
| dc.identifier.bibliographicCitation | Archives of Pharmacal Research, vol. 40, no. 11, pp. 1265-1270 | - |
| dc.identifier.doi | 10.1007/s12272-015-0659-7 | - |
| dc.subject.keyword | Acanthopanax senticosus | - |
| dc.subject.keyword | Araliaceae | - |
| dc.subject.keyword | Neo-lignan | - |
| dc.subject.keyword | PTP1B | - |
| dc.subject.local | acanthopanax senticosus | - |
| dc.subject.local | Acanthopanax senticosus (Rupr. & | - |
| dc.subject.local | Acanthopanax senticosus | - |
| dc.subject.local | araliaceae | - |
| dc.subject.local | Araliaceae | - |
| dc.subject.local | Neolignans | - |
| dc.subject.local | Neo-lignan | - |
| dc.subject.local | Neo-lignans | - |
| dc.subject.local | neolignan | - |
| dc.subject.local | Neolignan | - |
| dc.subject.local | PTP1B | - |
| dc.subject.local | PTP 1B | - |
| dc.description.journalClass | Y | - |
- Appears in Collections:
- Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
- Files in This Item:
There are no files associated with this item.
Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.