2-하이드록시-아릴아미드 유도체 또는 이의 약학적으로 허용가능한염, 이의제조방법및이를유효성분으로 함유하는암예방또는치료용약학적조성물

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dc.contributor.author김세미-
dc.contributor.author고동준-
dc.contributor.author남은희-
dc.contributor.author민혜진-
dc.date.accessioned2020-09-11T01:58:59Z-
dc.date.available2020-09-11T01:58:59Z-
dc.date.issued2016-02-23-
dc.identifier.other11030US-1-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/20644-
dc.description.abstractThe present invention relates to a 2-hydroxyarylamide derivative or a pharmaceutically acceptable salt thereof, a preparation method thereof, and a pharmaceutical composition for preventing or treating cancer comprising the same as an active ingredient. The 2-hydroxyarylamide derivative prepared by the present invention is excellent in the inhibition of the activity of TMPRSS4 serine protease and the suppression of the infiltration of TMPRSS4-expressed cancer cells, and thus can be useful as a composition for preventing or treating cancer by inhibiting TMPRSS4 over-expressed in cancer cells, particularly, colorectal cancer, lung cancer, breast cancer, prostate cancer, ovarian cancer, pancreatic cancer, or stomach cancer cells.-
dc.title2-하이드록시-아릴아미드 유도체 또는 이의 약학적으로 허용가능한염, 이의제조방법및이를유효성분으로 함유하는암예방또는치료용약학적조성물-
dc.title.alternative2-hydroxy-arylamide derivatives or pharmaceutically acceptable salts thereof, process for the preparation thereof, and pharmaceutical composition for the prevention and treatment of cancers containing the same as an active ingredient-
dc.typePatent-
dc.date.registration2016-02-23-
dc.contributor.affiliatedAuthor김세미-
dc.contributor.affiliatedAuthor고동준-
dc.contributor.affiliatedAuthor남은희-
dc.contributor.affiliatedAuthor민혜진-
dc.date.application2014-04-18-
dc.identifier.patentApplicationNumber14/256,808-
dc.identifier.patentRegistrationNumber9,266,872-
dc.publisher.location미국-
dc.contributor.assignee한국생명공학연구원-
dc.contributor.inventor김세미-
dc.description.patentCountryDivision국외-
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