Analysis and stability test of the extracts from ulmus parvifolia leaves = 참느릅나무(Ulmus parvifolia) 잎 추출물 분석 및 안정성 평가

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Title
Analysis and stability test of the extracts from ulmus parvifolia leaves = 참느릅나무(Ulmus parvifolia) 잎 추출물 분석 및 안정성 평가
Author(s)
Doo-Young Kim; Soobin Song; Iljoo Kim; S K Jeong; S Kim; Jung Hee KimHyun-Jae JangSei-Ryang OhHyung Won Ryu
Bibliographic Citation
Journal of Applied Biological Chemistry, vol. 63, no. 4, pp. 407-412
Publication Year
2020
Abstract
A simple and reliable HPLC method was developed to determine pharmacologically standard marker compounds of Ulmus parvifolia leaves. Standard markers were characterized with neochlorogenic acid (trans-5-O-caffeoylquinic acid, 5-CQA) and chlorogenic acid (trans-3-O-caffeoylquinic acid, 3-CQA) using NMR and UPLC-QTof-MS analysis. A method for qualitative/quantitative analysis of the leaves extracts were evaluated including two compounds by using HPLC. The stability test of 30% ethanolic extracts of the leaves sample and standard markers have been evaluated for six months. However, no significant changes in the content of the marker compounds of each extract was observed during the time of investigation.
Keyword
Caffeoylquinic acidUlmus parvifolia leavesUltra high performance liquid chromatographyStability
ISSN
1229-2737
Publisher
Springer
DOI
http://dx.doi.org/10.3839/jabc.2020.053
Type
Article
Appears in Collections:
Ochang Branch Institute > Division of National Bio-Infrastructure > Bio-Resource Central Bank > 1. Journal Articles
Ochang Branch Institute > 1. Journal Articles
Ochang Branch Institute > Natural Product Research Center > 1. Journal Articles
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