Total synthesis of agastaquinone, a diterpenoid quinone isolated from Agastache rugosa
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Title
Total synthesis of agastaquinone, a diterpenoid quinone isolated from Agastache rugosa
Author(s)
Sangku Lee; Jisu Yoo; J K Jung; J N Kim; M S Yoon
Bibliographic Citation
Synthetic Communications, vol. 51, no. 1, pp. 134-138
Publication Year
2021
Abstract
Agastaquinone is a tricyclic diterpenoid isolated from Agastache rugose. The first total synthesis of agastaquinone was accomplished based on intramolecular Friedel-Crafts acylation of aryl lactone followed by aromatization leading to the tricyclic phenol core structure as a key step.