In vitro induction of human antibody against hepatitis B virus surface antigen = B형 간염 바이러스 표면항원에 대한 항체의 유도

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Title
In vitro induction of human antibody against hepatitis B virus surface antigen = B형 간염 바이러스 표면항원에 대한 항체의 유도
Author(s)
Mi Young Han; Jae Wook Oh; Kyung Soo Nam; In Seong Choe; Tai Wha Chung
Bibliographic Citation
Korean Biochemical Journal, vol. 24, no. 6, pp. 550-554
Publication Year
1991
Abstract
Human peripheral blood lymphocytes (PBL) were isolated from the heparinized blood of antibody positive donors by centrifugation with Ficoll/Paque solution. The PBL were transformed with Epstein-Barr virus and the clones were screened for anti-HBsAg antibody production. Twenty-three percent of the total clones were HBsAg antibody positive. Among them, one clone showed stable antibody production. One of the polyclonal B cell activators, pokeweed mitogen, was effective for production of anti-HBsAg antibody and cell proliferation.
ISSN
0368-4881
Publisher
Korea Soc-Assoc-Inst
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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