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- Title
- Glucose-limited fed-batch culture of Escherichia coli for production of recombinant human interleukin-2 with the DO-stat method
- Author(s)
- Dong Jin Seo; Bong Hyun Chung; Young Bo Hwang; Young Hoon Park
- Bibliographic Citation
- Journal of Fermentation Bioengineering, vol. 74, no. 3, pp. 196-198
- Publication Year
- 1992
- Abstract
- Fed-batch culture employing the DO-stat method was carried out to produce recombinant human interleukin-2 in Escherichia coli. The concentration of interleukin-2 and final cell density in the fed-batch culture were 1.02 g/l and 60 OD (optical density), respectively. This represents a significant improvement in interleukin-2 production and final cell density over the equivalent values of batch fermentation.
- ISSN
- 0385-6380
- Publisher
- Soc Bioscience Bioengineering Japan
- DOI
- http://dx.doi.org/10.1016/0922-338X(92)90085-9
- Type
- Article
- Appears in Collections:
- 1. Journal Articles > Journal Articles
- Files in This Item:
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