Identification and production of flavonoids in a cell suspension culture of Scutellaria baicalensis G.

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Title
Identification and production of flavonoids in a cell suspension culture of Scutellaria baicalensis G.
Author(s)
Weon Taek Seo; Young Hoon Park; Tae Boo Choe
Bibliographic Citation
Plant Cell Reports, vol. 12, pp. 414-417
Publication Year
1993
Abstract
A high yielding cell line of Scutellaria baicalensis G. has successfully been developed to produce flavonoids. Major components of the flavonoids were identified as baicalin and wogonin-7-O-glucuronic acid by a series of instrumental analyses using UV, IR, MASS, and NMR. After 12 days in suspension culture, the cell growth reached 14 gDW/l, and baicalin and wogonin-7-O-glucuronic acid were obtained in concentrations of 2.9 g/l and 1.07 g/l, respectively. The culture temperature was found to be an important parameter for improving production yield of the flavonoids. The yield of baicalin was observed to increase to 4.2 g/l by shifting the temperature from 30 °C to 25 °C after 72 h of suspension culture.
Keyword
cell suspension cultureflavonoids (baicalin and wogonin-7-O-glucuonic acid) identification and productionscutellaria baicalensis G.
ISSN
0721-7714
Publisher
Springer
DOI
http://dx.doi.org/10.1007/BF00234703
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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