Open Access@KRIBBDivision of A.I. & Biomedical ResearchMetabolic Regulation Research Center1. Journal Articles
When gut fibroblasts feed epithelial cells to death
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Jong Woo Kim | - |
| dc.contributor.author | Byeong Jun Jeong | - |
| dc.contributor.author | Eun-Woo Lee | - |
| dc.date.accessioned | 2025-07-30T16:33:11Z | - |
| dc.date.available | 2025-07-30T16:33:11Z | - |
| dc.date.issued | 2025 | - |
| dc.identifier.issn | 2522-5812 | - |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/39090 | - |
| dc.description.abstract | Epithelial cell death driven by oxidative stress is a hallmark of inflammatory bowel disease (IBD), but the upstream triggers are unclear. A new study reveals that fibroblast-derived lipids enriched with polyunsaturated fatty acids induce epithelial ferroptosis. Genetic or pharmacological inhibition of fibroblast ACSL4 alleviates intestinal inflammation and injury in IBD models. | - |
| dc.publisher | Springer-Nature Pub Group | - |
| dc.title | When gut fibroblasts feed epithelial cells to death | - |
| dc.title.alternative | When gut fibroblasts feed epithelial cells to death | - |
| dc.type | Article | - |
| dc.citation.title | Nature Metabolism | - |
| dc.citation.number | 0 | - |
| dc.citation.endPage | 1309 | - |
| dc.citation.startPage | 1307 | - |
| dc.citation.volume | 7 | - |
| dc.contributor.affiliatedAuthor | Jong Woo Kim | - |
| dc.contributor.affiliatedAuthor | Byeong Jun Jeong | - |
| dc.contributor.affiliatedAuthor | Eun-Woo Lee | - |
| dc.contributor.alternativeName | 김종우 | - |
| dc.contributor.alternativeName | 정병준 | - |
| dc.contributor.alternativeName | 이은우 | - |
| dc.identifier.bibliographicCitation | Nature Metabolism, vol. 7, pp. 1307-1309 | - |
| dc.identifier.doi | 10.1038/s42255-025-01315-9 | - |
| dc.description.journalClass | Y | - |
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