Determination of isoprenyl and lavandulyl positions of flavonoids from Sophora flavescens by NMR experiment

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Title
Determination of isoprenyl and lavandulyl positions of flavonoids from Sophora flavescens by NMR experiment
Author(s)
Shi Yong Ryu; Hyun Sun Lee; Young Kyoon Kim; Sung Hoon Kim
Bibliographic Citation
Archives of Pharmacal Research, vol. 20, no. 5, pp. 491-495
Publication Year
1997
Abstract
All fifteen flavonoids (1-15) have been isolated from the roots of Sophora flavescens (Leguminosae) as active principles of the cytotoxic property toward human tumor cell lines such as A549, SK-OV-3, SK-Mel-2, XF498 and HCT15, in vitro. By means of spectral analyses, particularly by the aid of various two dimensional NMR experiments, all 1H-NMR and 13C-NMR signals of 1-15 were completely assigned, and thus the structures of 1-15 were established unambiguously.
Keyword
AntitumorCOLOCCytotoxicityKushenolNMRSophora flavescens
ISSN
0253-6269
Publisher
Pharmaceutical Soc Korea
DOI
http://dx.doi.org/10.1007/BF02973946
Type
Article
Appears in Collections:
Ochang Branch Institute > Natural Product Research Center > 1. Journal Articles
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