Open Access@KRIBBDivision of A.I. & Biomedical ResearchMicrobiome Convergence Research Center1. Journal Articles
Production of a Ras farnesyl protein transferase inhibitor from Bacillus licheniformis using Plackett-Burman design
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- Title
- Production of a Ras farnesyl protein transferase inhibitor from Bacillus licheniformis using Plackett-Burman design
- Author(s)
- Kwang Hee Son; Yong Guk Kwon; Kyung Sook Bae; Young Kook Kim; Byoung-Mog Kwon; Sung Uk Kim; Song Hae Bok
- Bibliographic Citation
- Biotechnology Letters, vol. 20, no. 2, pp. 149-151
- Publication Year
- 1998
- Abstract
- Compound CBR004 which inhibits Ras farnesyl protein transferase, was produced by Bacillus licheniformis KCTC0372BP. Potassium phosphate and Tryptone were selected as media components for the production of CBR004 among 6 culture-variables using Plackett-Burman design. The yield of CBR004 was 0.99 g/l in a stirred fermenter at the C/N ratio of 1.87.
- ISSN
- 0141-5492
- Publisher
- Springer
- Full Text Link
- http://dx.doi.org/10.1023/A:1005324407319
- Type
- Article
- Appears in Collections:
- Division of A.I. & Biomedical Research > Microbiome Convergence Research Center > 1. Journal Articles
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